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Peptide record

TPDB07500

Antibacterial Antifungal Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07500
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 DRAMP Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
KLLNLLPGLLAGIF
Physicochemical Analysis
C73H124N16O16
RDCEQHMSTWYV
L
1481.88
10.10
1
0
9
+1
-3.09
1.579
202.14
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
1
I
6
L
1
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 6 K: 1 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C73H124N16O16
1481.88
10.10
+1
-3.09
1.579
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
5% Hemolysis | 50 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Physicochemical and biological characterizations of Pxt peptides from amphibian (Xenopus tropicalis) skin. | J Biochem | 2016
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
5.2 %
Hemolytic
Hemolytic_activity: [Ref.26802742]5.2% Hemolysis against Rat erythrocytes at 50 µM.

Target

erythrocytes

Source & Reference

NA
DRAMP
J Biochem. 2016 Jun 159(6):619-29.