Back to search

Peptide record

TPDB07494

Antibacterial standard

14 amino acids

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB07494

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

AntiBP3 Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 14-aa standard natural antibacterial peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.

Sequence

YYHFWHRGVTKRSL

FASTA

>TPDB07494|Antibacterial|length=14
YYHFWHRGVTKRSL

Formula C88H124N26O19

Absent Amino Acids ANDCEQIMP

Common Amino Acids RHY

Mass 1850.12

PI 10.59

Basic Residues 5

Acidic Residues 0

Hydrophobic Residues 6

Net Charge +3

Boman Index -0.54

Hydrophobicity -0.993

Aliphatic Index 48.57

Half Life

Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min

Extinction Coefficient Cystines 8480

Absorbance 280nm 458.35

Polar Residues 4

number

Amino Acid Distribution

A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 2 I: 0 L: 1 K: 1 M: 0 F: 1 P: 0 S: 1 T: 1 W: 1 Y: 2 V: 1

Length

Formula

C88H124N26O19

Mass

1850.12

10.59

Net Charge

Boman Index

-0.54

Hydrophobicity

-0.993

Evidence 1 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 30 µM

Target

Target Organism Escherichia coli

Source & Reference

Database Source NA

Other

Evidence Text

Active against E. coli (MIC 30 uM), P. aeruginosa (MIC 60 uM) S. enterica (MIC 80 uM) K. pneumoniae (MIC 70 uM) S. aureus

Evidence 2 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 60 µM

Target

Target Organism Pseudomonas aeruginosa

Source & Reference

Database Source NA

Other

Evidence Text

Active against E. coli (MIC 30 uM), P. aeruginosa (MIC 60 uM) S. enterica (MIC 80 uM) K. pneumoniae (MIC 70 uM) S. aureus (MIC 60 uM) B. subtilis (

Evidence 3 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 80 µM

Target

Target Organism S. enterica

Source & Reference

Database Source NA

Other

Evidence Text

Active against E. coli (MIC 30 uM), P. aeruginosa (MIC 60 uM) S. enterica (MIC 80 uM) K. pneumoniae (MIC 70 uM) S. aureus (MIC 60 uM) B. subtilis (MIC 80 uM) S.pyogenes (M

Evidence 4 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 70 µM

Target

Target Organism Klebsiella pneumoniae

Source & Reference

Database Source NA

Other

Evidence Text

Active against E. coli (MIC 30 uM), P. aeruginosa (MIC 60 uM) S. enterica (MIC 80 uM) K. pneumoniae (MIC 70 uM) S. aureus (MIC 60 uM) B. subtilis (MIC 80 uM) S.pyogenes (MIC >100 uM) and E. faecali

Evidence 5 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 60 µM

Target

Target Organism Staphylococcus aureus

Source & Reference

Database Source NA

Other

Evidence Text

IC 30 uM), P. aeruginosa (MIC 60 uM) S. enterica (MIC 80 uM) K. pneumoniae (MIC 70 uM) S. aureus (MIC 60 uM) B. subtilis (MIC 80 uM) S.pyogenes (MIC >100 uM) and E. faecalis (MIC 70 uM).

Evidence 6 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 80 µM

Target

Target Organism B. subtilis

Source & Reference

Database Source NA

Other

Evidence Text

a (MIC 60 uM) S. enterica (MIC 80 uM) K. pneumoniae (MIC 70 uM) S. aureus (MIC 60 uM) B. subtilis (MIC 80 uM) S.pyogenes (MIC >100 uM) and E. faecalis (MIC 70 uM).

Evidence 7 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement >100 µM

Target

Target Organism S.pyogenes

Source & Reference

Database Source NA

Other

Evidence Text

a (MIC 80 uM) K. pneumoniae (MIC 70 uM) S. aureus (MIC 60 uM) B. subtilis (MIC 80 uM) S.pyogenes (MIC >100 uM) and E. faecalis (MIC 70 uM).

Evidence 8 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 70 µM

Target

Target Organism Enterococcus faecalis

Source & Reference

Database Source NA

Other

Evidence Text

MIC 70 uM) S. aureus (MIC 60 uM) B. subtilis (MIC 80 uM) S.pyogenes (MIC >100 uM) and E. faecalis (MIC 70 uM).