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Peptide record

TPDB07493

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07493
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
WRWRCRRRFCRWRW
Physicochemical Analysis
C101H145N39O15S2
ANDEQGHILKMPSTYV
R
2209.63
12.53
7
0
5
+7
-3.34
-1.950
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
22125
1001.30
2
Residue Composition
number
0
A
7
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 7 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
14
C101H145N39O15S2
2209.63
12.53
+7
-3.34
-1.950
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
10% Hemolysis | 64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial potency and selectivity of simplified symmetric-end peptides. | Biomaterials | 2014
Evidence 2 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.24621994] MHC10=64 µM against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
PLoS One. 2014 Mar 12 9(3):e91007. doi: 10.1371/journal.pone.0091007.