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Peptide record

TPDB07451

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07451
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
INWLKLGKKILGAI
Physicochemical Analysis
C76H131N19O16
RDCEQHMFPSTYV
ILK
1566.99
10.84
3
0
8
+3
-1.22
0.700
174.29
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
350.99
1
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
3
I
3
L
3
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 3 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
14
C76H131N19O16
1566.99
10.84
+3
-1.22
0.700
Evidence Records 6 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
75 µM
Hemolytic Cytotoxic
50% Hemolysis | 75 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
New potent antimicrobial peptides from the venom of Polistinae wasps and their analogs | Peptides | 2008
Evidence 2 Activity

Activity

IC50
Toxicity
20.60±1.07 µM
Cytotoxic
IC50 | 20.60±1.07 | µM | target cell: Human pancreas epithelial cells HPNE

Target

Human pancreas epithelial cells HPNE

Source & Reference

NA
DBAASP
Discovery of anticancer peptides from natural and generated sequences using deep learning. | Int J Biol Macromol | 2025
Evidence 3 Activity

Activity

IC50
Toxicity
>50 µM
Cytotoxic
IC50 | >50 | µM | target cell: Human umbilical vein endothelial cells HUVEC

Target

Human umbilical vein endothelial cells HUVEC

Source & Reference

NA
DBAASP
Discovery of anticancer peptides from natural and generated sequences using deep learning. | Int J Biol Macromol | 2025
Evidence 4 Activity

Activity

IC50
Toxicity
25.24±2.39 µM
Cytotoxic
IC50 | 25.24±2.39 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Discovery of anticancer peptides from natural and generated sequences using deep learning. | Int J Biol Macromol | 2025
Evidence 5 Activity

Activity

IC50
Toxicity
>50 µM
Cytotoxic
IC50 | >50 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Discovery of anticancer peptides from natural and generated sequences using deep learning. | Int J Biol Macromol | 2025
Evidence 6 Activity

Activity

50% Hemolysis
Toxicity
90 µM
Hemolytic Cytotoxic
50% Hemolysis | 90 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Discovery of anticancer peptides from natural and generated sequences using deep learning. | Int J Biol Macromol | 2025