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Peptide record

TPDB07450

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07450
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
INWKKLGKKILGAL
Physicochemical Analysis
C76H132N20O16
RDCEQHMFPSTYV
K
1582.01
11.00
4
0
7
+4
0.08
0.100
146.43
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
347.66
1
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
3
L
4
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 3 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
14
C76H132N20O16
1582.01
11.00
+4
0.08
0.100
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>140 µM
Hemolytic Cytotoxic
50% Hemolysis | >140 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
New potent antimicrobial peptides from the venom of Polistinae wasps and their analogs | Peptides | 2008