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Peptide record

TPDB07449

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07449
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
INWKKIFQKVKNLV
Physicochemical Analysis
C85H140N22O18
ARDCEGHMPSTY
K
1758.18
11.00
4
0
7
+4
1.36
-0.214
125.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
312.82
3
Residue Composition
number
0
A
0
R
2
N
0
D
0
C
0
E
1
Q
0
G
0
H
2
I
1
L
4
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 2 L: 1 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
14
C85H140N22O18
1758.18
11.00
+4
1.36
-0.214
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
50% Hemolysis | 100 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
New potent antimicrobial peptides from the venom of Polistinae wasps and their analogs. | Peptides | 2008
Evidence 2 Activity

Activity

IC50
Toxicity
100 µM
Hemolytic
Hemolytic_activity: [Ref.18375018]IC50 = 100 µM against rat red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2008 Jun 29(6):992-1003.