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Peptide record

TPDB07445

Antibacterial Antifungal Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB07445
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
INLKAIAPLAKKLL
Physicochemical Analysis
C72H132N18O16
RDCEQGHMFSTWYV
L
1505.95
10.84
3
0
9
+3
0.47
0.914
188.57
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
3
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
4
L
3
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 4 K: 3 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C72H132N18O16
1505.95
10.84
+3
0.47
0.914
Evidence Records 23 records
Evidence 1 Activity

Activity

MIC
Antibacterial
80 µM

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram-positive S. aureus ATCC25923 (MIC 80 uM), E.faecalis ATCC29212 (MIC >160 uM), S. aureus IS 10# (MIC 40 uM), S. aureus IS 37# (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
>160 µM

Target

Enterococcus faecalis ATCC29212

Source & Reference

dbAMP

Other

Active against Gram-positive S. aureus ATCC25923 (MIC 80 uM), E.faecalis ATCC29212 (MIC >160 uM), S. aureus IS 10# (MIC 40 uM), S. aureus IS 37# (MIC 80 uM), Gram-negative E.coli ATCC259
Evidence 3 Activity

Activity

MIC
Antibacterial
>160 µM

Target

E.coli ATCC25922

Source & Reference

dbAMP

Other

(MIC >160 uM), S. aureus IS 10# (MIC 40 uM), S. aureus IS 37# (MIC 80 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 40 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CM
Evidence 4 Activity

Activity

MIC
Antibacterial
40 µM

Target

Enterobacter cloacae ATCC13047

Source & Reference

dbAMP

Other

(MIC 40 uM), S. aureus IS 37# (MIC 80 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 40 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa
Evidence 5 Activity

Activity

MIC
Antibacterial
20 µM

Target

Klebsiella pneumoniae ATCC700603

Source & Reference

dbAMP

Other

C 80 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 40 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa ATCC27853 (MIC 10 uM), B. dysenteriae
Evidence 6 Activity

Activity

MIC
Antibacterial
10 µM

Target

B. pyocyaneus CMCCB1010

Source & Reference

dbAMP

Other

22 (MIC >160 uM), E. cloacae ATCC13047 (MIC 40 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa ATCC27853 (MIC 10 uM), B. dysenteriae (MIC 10 uM), E.coli IS 37# (MIC >160
Evidence 7 Activity

Activity

MIC
Antibacterial
10 µM

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP

Other

7 (MIC 40 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa ATCC27853 (MIC 10 uM), B. dysenteriae (MIC 10 uM), E.coli IS 37# (MIC >160 uM), E. coli IS 117# (MIC 80 uM), E.
Evidence 8 Activity

Activity

MIC
Antibacterial
10 µM

Target

B. dysenteriae

Source & Reference

dbAMP

Other

03 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa ATCC27853 (MIC 10 uM), B. dysenteriae (MIC 10 uM), E.coli IS 37# (MIC >160 uM), E. coli IS 117# (MIC 80 uM), E. coli IS 218# (MIC 80 uM), P
Evidence 9 Activity

Activity

MIC
Antibacterial
>160 µM

Target

C.albicans ATCC2002

Source & Reference

dbAMP

Other

(MIC 80 uM), P. aeruginosa IS 350# (MIC 80 uM), K.pneumoniae IS 59# (MIC >160 uM), fungi C.albicans ATCC2002 (MIC >160 uM), C. albicans ATCC90028 (MIC 20 uM), and C. parapsilosis ATCC22019 (MIC 20 uM). Updated 7/
Evidence 10 Activity

Activity

MIC
Antibacterial
20 µM

Target

Candida albicans ATCC90028

Source & Reference

dbAMP

Other

(MIC 80 uM), K.pneumoniae IS 59# (MIC >160 uM), fungi C.albicans ATCC2002 (MIC >160 uM), C. albicans ATCC90028 (MIC 20 uM), and C. parapsilosis ATCC22019 (MIC 20 uM). Updated 7/2021
Evidence 11 Activity

Activity

MIC
Antibacterial
20 µM

Target

C. parapsilosis ATCC22019

Source & Reference

dbAMP

Other

>160 uM), fungi C.albicans ATCC2002 (MIC >160 uM), C. albicans ATCC90028 (MIC 20 uM), and C. parapsilosis ATCC22019 (MIC 20 uM). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antifungal
80 µM

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram-positive S. aureus ATCC25923 (MIC 80 uM), E.faecalis ATCC29212 (MIC >160 uM), S. aureus IS 10# (MIC 40 uM), S. aureus IS 37# (MIC
Evidence 13 Activity

Activity

MIC
Antifungal
>160 µM

Target

Enterococcus faecalis ATCC29212

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram-positive S. aureus ATCC25923 (MIC 80 uM), E.faecalis ATCC29212 (MIC >160 uM), S. aureus IS 10# (MIC 40 uM), S. aureus IS 37# (MIC 80 uM), Gram-negative E.coli ATCC259
Evidence 14 Activity

Activity

MIC
Antifungal
>160 µM

Target

E.coli ATCC25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC >160 uM), S. aureus IS 10# (MIC 40 uM), S. aureus IS 37# (MIC 80 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 40 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CM
Evidence 15 Activity

Activity

MIC
Antifungal
40 µM

Target

Enterobacter cloacae ATCC13047

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 40 uM), S. aureus IS 37# (MIC 80 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 40 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa
Evidence 16 Activity

Activity

MIC
Antifungal
20 µM

Target

Klebsiella pneumoniae ATCC700603

Source & Reference

dbAMP CAFPdb Antifungipept

Other

C 80 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 40 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa ATCC27853 (MIC 10 uM), B. dysenteriae
Evidence 17 Activity

Activity

MIC
Antifungal
10 µM

Target

B. pyocyaneus CMCCB1010

Source & Reference

dbAMP CAFPdb Antifungipept

Other

22 (MIC >160 uM), E. cloacae ATCC13047 (MIC 40 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa ATCC27853 (MIC 10 uM), B. dysenteriae (MIC 10 uM), E.coli IS 37# (MIC >160
Evidence 18 Activity

Activity

MIC
Antifungal
10 µM

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP CAFPdb Antifungipept

Other

7 (MIC 40 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa ATCC27853 (MIC 10 uM), B. dysenteriae (MIC 10 uM), E.coli IS 37# (MIC >160 uM), E. coli IS 117# (MIC 80 uM), E.
Evidence 19 Activity

Activity

MIC
Antifungal
10 µM

Target

B. dysenteriae

Source & Reference

dbAMP CAFPdb Antifungipept

Other

03 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa ATCC27853 (MIC 10 uM), B. dysenteriae (MIC 10 uM), E.coli IS 37# (MIC >160 uM), E. coli IS 117# (MIC 80 uM), E. coli IS 218# (MIC 80 uM), P
Evidence 20 Activity

Activity

MIC
Antifungal
>160 µM

Target

C.albicans ATCC2002

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 80 uM), P. aeruginosa IS 350# (MIC 80 uM), K.pneumoniae IS 59# (MIC >160 uM), fungi C.albicans ATCC2002 (MIC >160 uM), C. albicans ATCC90028 (MIC 20 uM), and C. parapsilosis ATCC22019 (MIC 20 uM). Updated 7/
Evidence 21 Activity

Activity

MIC
Antifungal
20 µM

Target

Candida albicans ATCC90028

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 80 uM), K.pneumoniae IS 59# (MIC >160 uM), fungi C.albicans ATCC2002 (MIC >160 uM), C. albicans ATCC90028 (MIC 20 uM), and C. parapsilosis ATCC22019 (MIC 20 uM). Updated 7/2021
Evidence 22 Activity

Activity

MIC
Antifungal
20 µM

Target

C. parapsilosis ATCC22019

Source & Reference

dbAMP CAFPdb Antifungipept

Other

>160 uM), fungi C.albicans ATCC2002 (MIC >160 uM), C. albicans ATCC90028 (MIC 20 uM), and C. parapsilosis ATCC22019 (MIC 20 uM). Updated 7/2021
Evidence 23 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptides from the venom gland of the social wasp Vespa tropica. | Toxicon | 2013