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Peptide record

TPDB07439

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07439
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
TWLKKRRWKKVKPP
Physicochemical Analysis
C89H147N27O16
ANDCEQGHIMFSY
K
1851.32
12.45
7
0
4
+7
3.42
-1.871
48.57
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
11000
594.17
1
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
5
K
0
M
0
F
2
P
0
S
1
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 5 M: 0 F: 0 P: 2 S: 0 T: 1 W: 2 Y: 0 V: 1
Chemical Descriptors
14
C89H147N27O16
1851.32
12.45
+7
3.42
-1.871
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.02-0.03 µg/mL

Target

Pseudomonas aeruginosa ATCC 27853 or PAO1

Source & Reference

NA

Other

Active against P. aeruginosa ATCC 27853 or PAO1 (MIC 0.02-0.03 ug/ml), A-baumannii DSM3008 (MIC>64 ug/ml), K-pneumoniae ATCC 13883 (MIC>64 ug/ml), S-maltophili
Evidence 2 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

ug/ml), K-pneumoniae ATCC 13883 (MIC>64 ug/ml), S-maltophilia ATCC 13637 (MIC>64 ug/ml), E. coli ATCC 25922 (MIC 32 ug/ml), E-faecalis DSM 12956 (MIC>64 ug/ml), and S. aureus ATCC 29213 (MIC 64 ug/ml).
Evidence 3 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Staphylococcus aureus ATCC 29213

Source & Reference

NA

Other

IC>64 ug/ml), E. coli ATCC 25922 (MIC 32 ug/ml), E-faecalis DSM 12956 (MIC>64 ug/ml), and S. aureus ATCC 29213 (MIC 64 ug/ml).