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Peptide record

TPDB07431

Antibacterial Antifungal Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07431
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
HFLGTLVNLAKKIK
Physicochemical Analysis
C75H128N20O17
RDCEQMPSWY
LK
1581.97
10.84
4
0
7
+3
1.28
0.371
139.29
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
1
H
1
I
3
L
3
K
0
M
1
F
0
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 3 K: 3 M: 0 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
14
C75H128N20O17
1581.97
10.84
+3
1.28
0.371
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>500 µM
Hemolytic Cytotoxic
50% Hemolysis | >500 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Strategies for transformation of naturally-occurring amphibian antimicrobial peptides into therapeutically valuable anti-infective agents. | Methods | 2007