Back to search

Peptide record

TPDB07422

Antibacterial Antifungal Hemolysis Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB07422
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
INLKAITALAKKLL
Physicochemical Analysis
C71H132N18O17
RDCEQGHMFPSWYV
L
1509.94
10.84
3
0
9
+3
0.16
0.979
188.57
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
3
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
4
L
3
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 4 K: 3 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C71H132N18O17
1509.94
10.84
+3
0.16
0.979
Evidence Records 24 records
Evidence 1 Activity

Activity

MIC
Antibacterial
10 µM

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram-positive S. aureus ATCC25923 (MIC 10 uM), E. faecalis ATCC29212 (MIC 5 uM), S. aureus IS 10# (MIC 2.5 uM), S. aureus IS 37# (MIC 5
Evidence 2 Activity

Activity

MIC
Antibacterial
5 µM

Target

Enterococcus faecalis ATCC29212

Source & Reference

dbAMP

Other

Active against Gram-positive S. aureus ATCC25923 (MIC 10 uM), E. faecalis ATCC29212 (MIC 5 uM), S. aureus IS 10# (MIC 2.5 uM), S. aureus IS 37# (MIC 5 uM), Gram-negative E.coli ATCC259
Evidence 3 Activity

Activity

MIC
Antibacterial
>160 µM

Target

E.coli ATCC25922

Source & Reference

dbAMP

Other

212 (MIC 5 uM), S. aureus IS 10# (MIC 2.5 uM), S. aureus IS 37# (MIC 5 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 5 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMC
Evidence 4 Activity

Activity

MIC
Antibacterial
5 µM

Target

Enterobacter cloacae ATCC13047

Source & Reference

dbAMP

Other

(MIC 2.5 uM), S. aureus IS 37# (MIC 5 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 5 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa
Evidence 5 Activity

Activity

MIC
Antibacterial
20 µM

Target

Klebsiella pneumoniae ATCC700603

Source & Reference

dbAMP

Other

MIC 5 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 5 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa ATCC27853 (MIC 80 uM), B. dysenteriae
Evidence 6 Activity

Activity

MIC
Antibacterial
10 µM

Target

B. pyocyaneus CMCCB1010

Source & Reference

dbAMP

Other

922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 5 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa ATCC27853 (MIC 80 uM), B. dysenteriae (MIC 10 uM), E.coli IS 37# (MIC >160
Evidence 7 Activity

Activity

MIC
Antibacterial
80 µM

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP

Other

47 (MIC 5 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa ATCC27853 (MIC 80 uM), B. dysenteriae (MIC 10 uM), E.coli IS 37# (MIC >160 uM), E.coli IS 117# (MIC >160 uM), E
Evidence 8 Activity

Activity

MIC
Antibacterial
10 µM

Target

B. dysenteriae

Source & Reference

dbAMP

Other

03 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa ATCC27853 (MIC 80 uM), B. dysenteriae (MIC 10 uM), E.coli IS 37# (MIC >160 uM), E.coli IS 117# (MIC >160 uM), E.coli IS 218# (MIC >160 uM),
Evidence 9 Activity

Activity

MIC
Antibacterial
5 µM

Target

Candida albicans ATCC2002

Source & Reference

dbAMP

Other

(MIC >160 uM), P. aeruginosa IS 350# (MIC 10 uM), K. pneumoniae IS 59# (MIC 20 uM), fungi C. albicans ATCC2002 (MIC 5 uM), C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 2.5 uM). Updated 7
Evidence 10 Activity

Activity

MIC
Antibacterial
10 µM

Target

Candida albicans ATCC90028

Source & Reference

dbAMP

Other

50# (MIC 10 uM), K. pneumoniae IS 59# (MIC 20 uM), fungi C. albicans ATCC2002 (MIC 5 uM), C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 2.5 uM). Updated 7/2021
Evidence 11 Activity

Activity

MIC
Antibacterial
2.5 µM

Target

C. parapsilosis ATCC22019

Source & Reference

dbAMP

Other

MIC 20 uM), fungi C. albicans ATCC2002 (MIC 5 uM), C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 2.5 uM). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antifungal
10 µM

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram-positive S. aureus ATCC25923 (MIC 10 uM), E. faecalis ATCC29212 (MIC 5 uM), S. aureus IS 10# (MIC 2.5 uM), S. aureus IS 37# (MIC 5
Evidence 13 Activity

Activity

MIC
Antifungal
5 µM

Target

Enterococcus faecalis ATCC29212

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram-positive S. aureus ATCC25923 (MIC 10 uM), E. faecalis ATCC29212 (MIC 5 uM), S. aureus IS 10# (MIC 2.5 uM), S. aureus IS 37# (MIC 5 uM), Gram-negative E.coli ATCC259
Evidence 14 Activity

Activity

MIC
Antifungal
>160 µM

Target

E.coli ATCC25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

212 (MIC 5 uM), S. aureus IS 10# (MIC 2.5 uM), S. aureus IS 37# (MIC 5 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 5 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMC
Evidence 15 Activity

Activity

MIC
Antifungal
5 µM

Target

Enterobacter cloacae ATCC13047

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 2.5 uM), S. aureus IS 37# (MIC 5 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 5 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa
Evidence 16 Activity

Activity

MIC
Antifungal
20 µM

Target

Klebsiella pneumoniae ATCC700603

Source & Reference

dbAMP CAFPdb Antifungipept

Other

MIC 5 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 5 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa ATCC27853 (MIC 80 uM), B. dysenteriae
Evidence 17 Activity

Activity

MIC
Antifungal
10 µM

Target

B. pyocyaneus CMCCB1010

Source & Reference

dbAMP CAFPdb Antifungipept

Other

922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 5 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa ATCC27853 (MIC 80 uM), B. dysenteriae (MIC 10 uM), E.coli IS 37# (MIC >160
Evidence 18 Activity

Activity

MIC
Antifungal
80 µM

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP CAFPdb Antifungipept

Other

47 (MIC 5 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa ATCC27853 (MIC 80 uM), B. dysenteriae (MIC 10 uM), E.coli IS 37# (MIC >160 uM), E.coli IS 117# (MIC >160 uM), E
Evidence 19 Activity

Activity

MIC
Antifungal
10 µM

Target

B. dysenteriae

Source & Reference

dbAMP CAFPdb Antifungipept

Other

03 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 10 uM), P. aeruginosa ATCC27853 (MIC 80 uM), B. dysenteriae (MIC 10 uM), E.coli IS 37# (MIC >160 uM), E.coli IS 117# (MIC >160 uM), E.coli IS 218# (MIC >160 uM),
Evidence 20 Activity

Activity

MIC
Antifungal
5 µM

Target

Candida albicans ATCC2002

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC >160 uM), P. aeruginosa IS 350# (MIC 10 uM), K. pneumoniae IS 59# (MIC 20 uM), fungi C. albicans ATCC2002 (MIC 5 uM), C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 2.5 uM). Updated 7
Evidence 21 Activity

Activity

MIC
Antifungal
10 µM

Target

Candida albicans ATCC90028

Source & Reference

dbAMP CAFPdb Antifungipept

Other

50# (MIC 10 uM), K. pneumoniae IS 59# (MIC 20 uM), fungi C. albicans ATCC2002 (MIC 5 uM), C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 2.5 uM). Updated 7/2021
Evidence 22 Activity

Activity

MIC
Antifungal
2.5 µM

Target

C. parapsilosis ATCC22019

Source & Reference

dbAMP CAFPdb Antifungipept

Other

MIC 20 uM), fungi C. albicans ATCC2002 (MIC 5 uM), C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 2.5 uM). Updated 7/2021
Evidence 23 Activity

Activity

25% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
25% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptides from the venom gland of the social wasp Vespa tropica. | Toxicon | 2013
Evidence 24 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.