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Peptide record

TPDB07414

Antibacterial Hemolysis Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07414
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RRRCPIVVIRVCRR
Physicochemical Analysis
C74H140N32O15S2
ANDEQGHLKMFSTWY
R
1782.25
12.40
6
0
5
+6
4.42
-0.143
117.86
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
125
7.01
2
Residue Composition
number
0
A
6
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
2
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
14
C74H140N32O15S2
1782.25
12.40
+6
4.42
-0.143
Evidence Records 3 records
Evidence 1 Activity

Activity

MHC
Toxicity
64 µg/mL
Hemolytic Cytotoxic
MHC | 64 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Improved derivatives of bactenecin, a cyclic dodecameric antimicrobial cationic peptide. | Antimicrob Agents Chemother | 1999
Evidence 2 Activity

Activity

MHC
Toxicity
16 µg/mL
Hemolytic Cytotoxic
MHC | 16 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Improved derivatives of bactenecin, a cyclic dodecameric antimicrobial cationic peptide. | Antimicrob Agents Chemother | 1999
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis