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Peptide record

TPDB07409

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07409
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 DRAMP Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, DRAMP, and Peptipedia, with an available 3D structural model.
Sequence
LNLKALLAVAKKI
Physicochemical Analysis
C66H123N17O15
RDCEQGHMFPSTWY
L
1394.81
10.84
3
0
9
+3
0.40
1.085
195.38
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
3
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
4
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 4 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
13
C66H123N17O15
1394.81
10.84
+3
0.40
1.085
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
0% Hemolysis | 256 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Newly designed antimicrobial peptides with potent bioactivity and enhanced cell selectivity prevent and reverse rifampin resistance in Gram-negative bacteria. | Eur J Pharm Sci | 2020
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
0 %
Hemolytic
Hemolytic_activity: [Ref.33285267]0% hemolysis against mouse erythrocytes at 256 µM.

Target

erythrocytes

Source & Reference

NA
DRAMP
Eur J Pharm Sci. 2021 Mar 1 158:105665.