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Peptide record

TPDB07408

Antibacterial Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07408
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GLFDIIKKIAASF
Physicochemical Analysis
C69H111N15O17
RNCEQHMPTWYV
I
1422.73
9.88
2
1
8
+1
-0.74
1.077
135.38
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
2
A
0
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
3
I
1
L
2
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 1 K: 2 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C69H111N15O17
1422.73
9.88
+1
-0.74
1.077
Evidence Records 4 records
Evidence 1 Activity

Activity

40.2% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
40.2% Hemolysis | 256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Alanine Scanning Studies of the Antimicrobial Peptide Aurein 1.2 | Probiotics Antimicrob Proteins | 2019
Evidence 2 Activity

Activity

11.9% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
11.9% Hemolysis | 128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Alanine Scanning Studies of the Antimicrobial Peptide Aurein 1.2 | Probiotics Antimicrob Proteins | 2019
Evidence 3 Activity

Activity

2.9% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
2.9% Hemolysis | 64 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Alanine Scanning Studies of the Antimicrobial Peptide Aurein 1.2 | Probiotics Antimicrob Proteins | 2019
Evidence 4 Activity

Activity

0.4% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
0.4% Hemolysis | 32 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Alanine Scanning Studies of the Antimicrobial Peptide Aurein 1.2 | Probiotics Antimicrob Proteins | 2019