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Peptide record

TPDB07366

Antibacterial Anticancer Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07366
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RWGKWFKKNSHLS
Physicochemical Analysis
C79H116N24O17
ADCEQIMPTYV
K
1673.94
11.73
5
0
4
+4
0.04
-1.546
30.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
657.13
3
Residue Composition
number
0
A
1
R
1
N
0
D
0
C
0
E
0
Q
1
G
1
H
0
I
1
L
3
K
0
M
1
F
0
P
2
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 1 K: 3 M: 0 F: 1 P: 0 S: 2 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
13
C79H116N24O17
1673.94
11.73
+4
0.04
-1.546
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
Toxicity
>100 µM
Cytotoxic
IC50 | >100 | µM | target cell: Human umbilical vein endothelial cells HUVEC

Target

Human umbilical vein endothelial cells HUVEC

Source & Reference

NA
DBAASP
Re-engineering Antimicrobial Peptides into Oncolytics Targeting Drug-Resistant Ovarian Cancers. | Cell Mol Bioeng | 2020
Evidence 2 Activity

Activity

IC50
Toxicity
>100 µM
Cytotoxic
IC50 | >100 | µM | target cell: Human lung normal epithelial cells NL20

Target

Human lung normal epithelial cells NL20

Source & Reference

NA
DBAASP
Re-engineering Antimicrobial Peptides into Oncolytics Targeting Drug-Resistant Ovarian Cancers. | Cell Mol Bioeng | 2020
Evidence 3 Activity

Activity

IC50
Toxicity
100 µM
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: HUVEC: IC50>100 µM NL20: IC50>100 µM

Target

erythrocytes

Source & Reference

NA
DRAMP
Cell Mol Bioeng. 2020 Jun 24 13(5):447-461.