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Peptide record

TPDB07365

Antibacterial Antifungal Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07365
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FLQKIIGALGKLF
Physicochemical Analysis
C72H118N16O15
RNDCEHMPSTWYV
L
1447.83
10.60
2
0
8
+2
-2.15
1.208
157.69
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
1
Q
2
G
0
H
2
I
3
L
2
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 2 L: 3 K: 2 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C72H118N16O15
1447.83
10.60
+2
-2.15
1.208
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
16 µM
Hemolytic Cytotoxic
10% Hemolysis | 16 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The Analogs of Temporin-GHa Exhibit a Broader Spectrum of Antimicrobial Activity and a Stronger Antibiofilm Potential Against Staphylococcus aureus. | Molecules | 2019
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
66 µM
Hemolytic Cytotoxic
50% Hemolysis | 66 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The Analogs of Temporin-GHa Exhibit a Broader Spectrum of Antimicrobial Activity and a Stronger Antibiofilm Potential Against Staphylococcus aureus. | Molecules | 2019
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis