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Peptide record

TPDB07355

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07355
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
IFSAIAGLLSNLL
Physicochemical Analysis
C63H106N14O17
RDCEQHKMPTWYV
L
1331.62
6.02
0
0
9
-0
-3.64
1.931
195.38
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
3
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
4
L
0
K
0
M
1
F
0
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 4 K: 0 M: 0 F: 1 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C63H106N14O17
1331.62
6.02
-0
-3.64
1.931
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
611.8 µM
Hemolytic Cytotoxic
10% Hemolysis | 611.8 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Non-disulfide-Bridge Peptide 5.5 from the Scorpion Hadrurus gertschi Inhibits the Growth of Mycobacterium abscessus subsp. massiliense. | Front Microbiol | 2017
Evidence 2 Activity

Activity

39% Hemolysis
Toxicity
1600 µM
Hemolytic Cytotoxic
39% Hemolysis | 1600 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Non-disulfide-Bridge Peptide 5.5 from the Scorpion Hadrurus gertschi Inhibits the Growth of Mycobacterium abscessus subsp. massiliense. | Front Microbiol | 2017
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.17506894]Weak hemolytic activity against sheep red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
BMC Genomics. 2007 May 16 8:119.