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Peptide record

TPDB07350

Antibacterial Anticancer Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07350
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, and Peptipedia, with an available 3D structural model.
Sequence
RRRYIGRYVRFWK
Physicochemical Analysis
C87H134N30O16
ANDCEQHLMPST
R
1856.21
12.24
6
0
6
+6
-0.05
-1.446
52.31
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
8480
456.84
2
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
0
L
1
K
0
M
1
F
0
P
0
S
0
T
1
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 1 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 2 V: 1
Chemical Descriptors
13
C87H134N30O16
1856.21
12.24
+6
-0.05
-1.446
Evidence Records 2 records
Evidence 1 Activity

Activity

<1% Hemolysis
Toxicity
540 µM
Hemolytic Cytotoxic
<1% Hemolysis | 540 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
D-Amino Acid Analogues of the Antimicrobial Peptide CDT Exhibit Anti-Cancer Properties in A549, a Human Lung Adenocarcinoma Cell Line. | Protein Pept Lett | 2017
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
1 %
Hemolytic Cytotoxic
Hemolytic_activity: Sheep erythrocytes: <1% Hemolysis=540µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Protein Pept Lett. 2017 24(7):590-598.