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Peptide record

TPDB07337

Antibacterial Anticancer Antifungal Antiviral Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07337
Antibacterial Anticancer Antifungal Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb AI4AVP dbAMP 3.0 DRAVP 2.0 APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
IFKAIWSGIKSLF
Physicochemical Analysis
C76H116N16O16
RNDCEQHMPTYV
I
1509.85
10.60
2
0
8
+2
-3.52
1.077
127.69
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
364.27
2
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
1
L
2
K
0
M
2
F
0
P
2
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 1 K: 2 M: 0 F: 2 P: 0 S: 2 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C76H116N16O16
1509.85
10.60
+2
-3.52
1.077
Evidence Records 11 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2 µM

Target

M. luteus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against M. luteus (MIC 2 uM), E. coli (15 uM), L. grayi (2 uM), L. fleischmannii, L. monocytogenes (MIC 2 uM) and Hep
Evidence 2 Activity

Activity

MIC
Antibacterial
2 µM

Target

L. monocytogenes

Source & Reference

dbAMP DRAMP

Other

Active against M. luteus (MIC 2 uM), E. coli (15 uM), L. grayi (2 uM), L. fleischmannii, L. monocytogenes (MIC 2 uM) and Hepatitis C virus (HCV) (IC50 5 uM). It works on membranes. Found in multiple specie
Evidence 3 Activity

Activity

MIC
Antifungal
2 µM

Target

M. luteus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against M. luteus (MIC 2 uM), E. coli (15 uM), L. grayi (2 uM), L. fleischmannii, L. monocytogenes (MIC 2 uM) and Hep
Evidence 4 Activity

Activity

MIC
Antifungal
2 µM

Target

L. monocytogenes

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against M. luteus (MIC 2 uM), E. coli (15 uM), L. grayi (2 uM), L. fleischmannii, L. monocytogenes (MIC 2 uM) and Hepatitis C virus (HCV) (IC50 5 uM). It works on membranes. Found in multiple specie
Evidence 5 Activity

Activity

MIC
Antiviral
2 µM

Target

M. luteus

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
Active against M. luteus (MIC 2 uM), E. coli (15 uM), L. grayi (2 uM), L. fleischmannii, L. monocytogenes (MIC 2 uM) and Hep
Evidence 6 Activity

Activity

MIC
Antiviral
2 µM

Target

L. monocytogenes

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Active against M. luteus (MIC 2 uM), E. coli (15 uM), L. grayi (2 uM), L. fleischmannii, L. monocytogenes (MIC 2 uM) and Hepatitis C virus (HCV) (IC50 5 uM). It works on membranes. Found in multiple specie
Evidence 7 Activity

Activity

EC50
Toxicity
9.71 µM
Cytotoxic
EC50 | 9.71 | µM | target cell: Baby Hamster Kidney cells BHK-21

Target

Baby Hamster Kidney cells BHK-21

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 8 Activity

Activity

10% Hemolysis
Toxicity
11.944 µM
Hemolytic Cytotoxic
10% Hemolysis | 11.944 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 9 Activity

Activity

50% Hemolysis
Toxicity
59.25 µM
Hemolytic Cytotoxic
50% Hemolysis | 59.25 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 10 Activity

Activity

90% Hemolysis
Toxicity
293.90 µM
Hemolytic Cytotoxic
90% Hemolysis | 293.90 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 11 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.