TPDB

3D PDB MODEL

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TPDB ID TPDB07333

Activity

Antibacterial Anticancer Antifungal Antiparasitic Antiviral

Activity_category_statistics

Anti-infective peptides Cancer-related peptides

Database_Source

AntiBP3 dbAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb

Sequence_Type

standard

Has_Modification No

Description A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.

Sequence

FLPLIGKILGTIL

FASTA

>TPDB07333|Antibacterial;Anticancer;Antifungal;Antiparasitic;Antiviral|length=13
FLPLIGKILGTIL

Formula C70H120N14O15

Absent Amino Acids ARNDCEQHMSWYV

Common Amino Acids L

Mass 1397.81

PI 10.10

Basic Residues 1

Acidic Residues 0

Hydrophobic Residues 8

Net Charge +1

Boman Index -2.70

Hydrophobicity 1.885

Aliphatic Index 210.00

Half Life

Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 0

Absorbance 280nm 0.00

Polar Residues 1

number

0

A

0

R

0

N

0

D

0

C

0

E

0

Q

2

G

0

H

3

I

4

L

1

K

0

M

1

F

1

P

0

S

1

T

0

W

0

Y

0

V

Amino Acid Distribution

A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 4 K: 1 M: 0 F: 1 P: 1 S: 0 T: 1 W: 0 Y: 0 V: 0

Length

13

Formula

C70H120N14O15

Mass

1397.81

PI

10.10

Net Charge

+1

Boman Index

-2.70

Hydrophobicity

1.885

Evidence 1 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 5 µM

Target

Target Organism Staphylococcus aureus

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.

Evidence Text

Active against S. aureus (MIC 5 uM). Updated 5/2018.

Evidence 2 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 5 µM

Target

Target Organism Staphylococcus aureus

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.

Evidence Text

Active against S. aureus (MIC 5 uM). Updated 5/2018.

Evidence 3 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 5 µM

Target

Target Organism Staphylococcus aureus

Source & Reference

Database Source NA

Other

Evidence Text

Active against S. aureus (MIC 5 uM). Updated 5/2018.

Evidence 4 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 5 µM

Target

Target Organism Staphylococcus aureus

Source & Reference

Database Source NA

Other

Evidence Text

Active against S. aureus (MIC 5 uM). Updated 5/2018.