Back to search

Peptide record

TPDB07332

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB07332
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLPGLIAGIAKML
Physicochemical Analysis
C65H110N14O14S1
RNDCEQHSTWYV
L
1343.73
10.10
1
0
9
+1
-2.54
1.723
165.38
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
3
L
1
K
1
M
1
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 3 K: 1 M: 1 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C65H110N14O14S1
1343.73
10.10
+1
-2.54
1.723
Evidence Records 10 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12.5 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram+ S. aureus (MIC 12.5 ug/ml) and B. subtilis (MIC 25 ug/ml). No activity detected against Gram- bacteria P.fluorescens
Evidence 2 Activity

Activity

MIC
Antibacterial
25 µg/mL

Target

B. subtilis

Source & Reference

dbAMP DRAMP

Other

Active against Gram+ S. aureus (MIC 12.5 ug/ml) and B. subtilis (MIC 25 ug/ml). No activity detected against Gram- bacteria P.fluorescens and fungi C.albicans.
Evidence 3 Activity

Activity

MIC
Antifungal
12.5 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram+ S. aureus (MIC 12.5 ug/ml) and B. subtilis (MIC 25 ug/ml). No activity detected against Gram- bacteria P.fluorescens
Evidence 4 Activity

Activity

MIC
Antifungal
25 µg/mL

Target

B. subtilis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against Gram+ S. aureus (MIC 12.5 ug/ml) and B. subtilis (MIC 25 ug/ml). No activity detected against Gram- bacteria P.fluorescens and fungi C.albicans.
Evidence 5 Activity

Activity

MIC
Antiparasitic
12.5 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram+ S. aureus (MIC 12.5 ug/ml) and B. subtilis (MIC 25 ug/ml). No activity detected against Gram- bacteria P.fluorescens
Evidence 6 Activity

Activity

MIC
Antiparasitic
25 µg/mL

Target

B. subtilis

Source & Reference

DRAMP

Other

Active against Gram+ S. aureus (MIC 12.5 ug/ml) and B. subtilis (MIC 25 ug/ml). No activity detected against Gram- bacteria P.fluorescens and fungi C.albicans.
Evidence 7 Activity

Activity

MIC
Antiviral
12.5 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram+ S. aureus (MIC 12.5 ug/ml) and B. subtilis (MIC 25 ug/ml). No activity detected against Gram- bacteria P.fluorescens
Evidence 8 Activity

Activity

MIC
Antiviral
25 µg/mL

Target

B. subtilis

Source & Reference

DRAMP

Other

Active against Gram+ S. aureus (MIC 12.5 ug/ml) and B. subtilis (MIC 25 ug/ml). No activity detected against Gram- bacteria P.fluorescens and fungi C.albicans.
Evidence 9 Activity

Activity

50% Hemolysis
Toxicity
>100 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >100 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Isolation, characterization and molecular cloning of new antimicrobial peptides belonging to the brevinin-1 and temporin families from the skin of Hylarana latouchii (Anura: Ranidae). | Biochimie | 2009
Evidence 10 Activity

Activity

LD50
Toxicity
100 µg/mL
Hemolytic
Hemolytic_activity: [Ref:19340924]LD50>100 µg/ml against rabbit red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochimie. 2009 Apr 91(4):540-547.