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Peptide record

TPDB07331

Antibacterial Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07331
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
FLPFVGNLLKGLL
Physicochemical Analysis
C72H115N15O15
ARDCEQHIMSTWY
L
1430.80
10.10
1
0
8
+1
-3.11
1.462
172.31
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
5
L
1
K
0
M
2
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 5 K: 1 M: 0 F: 2 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
13
C72H115N15O15
1430.80
10.10
+1
-3.11
1.462
Evidence Records 19 records
Evidence 1 Activity

Activity

MIC
Antibacterial
19 µM

Target

B. licheniformis X39 IS

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Primarily active against Gram-positive bacteria: R. rhodochrous X15 (IS) (MIC 9 uM), B. licheniformis X39 IS (MIC 19 uM), E. faecalis 981 (MIC 19 uM), S. carnosus KHS IS (MIC 19 uM), S. aureus ATCC 25923 (MIC 9
Evidence 2 Activity

Activity

MIC
Antibacterial
19 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP

Other

sitive bacteria: R. rhodochrous X15 (IS) (MIC 9 uM), B. licheniformis X39 IS (MIC 19 uM), E. faecalis 981 (MIC 19 uM), S. carnosus KHS IS (MIC 19 uM), S. aureus ATCC 25923 (MIC 9 uM), E.coli ATCC 25922 (MIC
Evidence 3 Activity

Activity

MIC
Antibacterial
19 µM

Target

S. carnosus KHS IS

Source & Reference

dbAMP

Other

us X15 (IS) (MIC 9 uM), B. licheniformis X39 IS (MIC 19 uM), E. faecalis 981 (MIC 19 uM), S. carnosus KHS IS (MIC 19 uM), S. aureus ATCC 25923 (MIC 9 uM), E.coli ATCC 25922 (MIC >150 uM), P.aeruginosa CGMCC 1.5
Evidence 4 Activity

Activity

MIC
Antibacterial
9 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

niformis X39 IS (MIC 19 uM), E. faecalis 981 (MIC 19 uM), S. carnosus KHS IS (MIC 19 uM), S. aureus ATCC 25923 (MIC 9 uM), E.coli ATCC 25922 (MIC >150 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 110
Evidence 5 Activity

Activity

MIC
Antibacterial
>150 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP

Other

aecalis 981 (MIC 19 uM), S. carnosus KHS IS (MIC 19 uM), S. aureus ATCC 25923 (MIC 9 uM), E.coli ATCC 25922 (MIC >150 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 11053 (IS)(MIC >150 uM), K.pneumonia
Evidence 6 Activity

Activity

MIC
Antibacterial
>150 µM

Target

K.pneumoniae 08040724 IS

Source & Reference

dbAMP

Other

IC >150 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 11053 (IS)(MIC >150 uM), K.pneumoniae 08040724 IS (MIC >150 uM), P. faecalis X29 IS (MIC 75 uM), S. rubidaea X01 IS (MIC 75 uM), C.albicans ATCC 10231 (M
Evidence 7 Activity

Activity

MIC
Antibacterial
75 µM

Target

P. faecalis X29 IS

Source & Reference

dbAMP

Other

C >150 uM), P.aeruginosa 11053 (IS)(MIC >150 uM), K.pneumoniae 08040724 IS (MIC >150 uM), P. faecalis X29 IS (MIC 75 uM), S. rubidaea X01 IS (MIC 75 uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223 I
Evidence 8 Activity

Activity

MIC
Antibacterial
75 µM

Target

S. rubidaea X01 IS

Source & Reference

dbAMP

Other

IS)(MIC >150 uM), K.pneumoniae 08040724 IS (MIC >150 uM), P. faecalis X29 IS (MIC 75 uM), S. rubidaea X01 IS (MIC 75 uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223 IS (MIC 9 uM). IS: Isolated strai
Evidence 9 Activity

Activity

MIC
Antibacterial
>150 µM

Target

C.albicans ATCC 10231

Source & Reference

dbAMP

Other

8040724 IS (MIC >150 uM), P. faecalis X29 IS (MIC 75 uM), S. rubidaea X01 IS (MIC 75 uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223 IS (MIC 9 uM). IS: Isolated strain.
Evidence 10 Activity

Activity

MIC
Antifungal
19 µM

Target

B. licheniformis X39 IS

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Primarily active against Gram-positive bacteria: R. rhodochrous X15 (IS) (MIC 9 uM), B. licheniformis X39 IS (MIC 19 uM), E. faecalis 981 (MIC 19 uM), S. carnosus KHS IS (MIC 19 uM), S. aureus ATCC 25923 (MIC 9
Evidence 11 Activity

Activity

MIC
Antifungal
19 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP CAFPdb Antifungipept

Other

sitive bacteria: R. rhodochrous X15 (IS) (MIC 9 uM), B. licheniformis X39 IS (MIC 19 uM), E. faecalis 981 (MIC 19 uM), S. carnosus KHS IS (MIC 19 uM), S. aureus ATCC 25923 (MIC 9 uM), E.coli ATCC 25922 (MIC
Evidence 12 Activity

Activity

MIC
Antifungal
19 µM

Target

S. carnosus KHS IS

Source & Reference

dbAMP CAFPdb Antifungipept

Other

us X15 (IS) (MIC 9 uM), B. licheniformis X39 IS (MIC 19 uM), E. faecalis 981 (MIC 19 uM), S. carnosus KHS IS (MIC 19 uM), S. aureus ATCC 25923 (MIC 9 uM), E.coli ATCC 25922 (MIC >150 uM), P.aeruginosa CGMCC 1.5
Evidence 13 Activity

Activity

MIC
Antifungal
9 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

niformis X39 IS (MIC 19 uM), E. faecalis 981 (MIC 19 uM), S. carnosus KHS IS (MIC 19 uM), S. aureus ATCC 25923 (MIC 9 uM), E.coli ATCC 25922 (MIC >150 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 110
Evidence 14 Activity

Activity

MIC
Antifungal
>150 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

aecalis 981 (MIC 19 uM), S. carnosus KHS IS (MIC 19 uM), S. aureus ATCC 25923 (MIC 9 uM), E.coli ATCC 25922 (MIC >150 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 11053 (IS)(MIC >150 uM), K.pneumonia
Evidence 15 Activity

Activity

MIC
Antifungal
>150 µM

Target

K.pneumoniae 08040724 IS

Source & Reference

dbAMP CAFPdb Antifungipept

Other

IC >150 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 11053 (IS)(MIC >150 uM), K.pneumoniae 08040724 IS (MIC >150 uM), P. faecalis X29 IS (MIC 75 uM), S. rubidaea X01 IS (MIC 75 uM), C.albicans ATCC 10231 (M
Evidence 16 Activity

Activity

MIC
Antifungal
75 µM

Target

P. faecalis X29 IS

Source & Reference

dbAMP CAFPdb Antifungipept

Other

C >150 uM), P.aeruginosa 11053 (IS)(MIC >150 uM), K.pneumoniae 08040724 IS (MIC >150 uM), P. faecalis X29 IS (MIC 75 uM), S. rubidaea X01 IS (MIC 75 uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223 I
Evidence 17 Activity

Activity

MIC
Antifungal
75 µM

Target

S. rubidaea X01 IS

Source & Reference

dbAMP CAFPdb Antifungipept

Other

IS)(MIC >150 uM), K.pneumoniae 08040724 IS (MIC >150 uM), P. faecalis X29 IS (MIC 75 uM), S. rubidaea X01 IS (MIC 75 uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223 IS (MIC 9 uM). IS: Isolated strai
Evidence 18 Activity

Activity

MIC
Antifungal
>150 µM

Target

C.albicans ATCC 10231

Source & Reference

dbAMP CAFPdb Antifungipept

Other

8040724 IS (MIC >150 uM), P. faecalis X29 IS (MIC 75 uM), S. rubidaea X01 IS (MIC 75 uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223 IS (MIC 9 uM). IS: Isolated strain.
Evidence 19 Activity

Activity

50% Hemolysis
Toxicity
>150 µM
Hemolytic Cytotoxic
50% Hemolysis | >150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization of diverse antimicrobial peptides in skin secretions of Chungan torrent frog Amolops chunganensis | Peptides | 2012