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Peptide record

TPDB07313

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07313
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb APD_hemolytic PD_Hemolysis ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ILPILGNLLNGLL
Physicochemical Analysis
C65H115N15O16
ARDCEQHKMFSTWYV
L
1362.72
6.02
0
0
8
-0
-2.67
1.723
240.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
0
R
2
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
6
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 6 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C65H115N15O16
1362.72
6.02
-0
-2.67
1.723
Evidence Records 4 records
Evidence 1 Activity

Activity

HC50
Hemolysis
300 µM
[Ref:15003829]HC50>300 µM against washed human erythrocytes

Target

washed human erythrocytes

Source & Reference

Hemolytik APD_hemolytic PD_Hemolysis
DRAMP4
Regul. Pept 2004 118: 135-141.

Other

Source Activity Label Source Definition
Hemolysis
APD_hemolytic APD hemolytic peptide annotation. Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
>300 µM
Hemolytic Cytotoxic
50% Hemolysis | >300 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A family of brevinin-2 peptides with potent activity against Pseudomonas aeruginosa from the skin of the Hokkaido frog, Rana pirica. | Regul Pept | 2004
Evidence 3 Activity

Activity

HC50
Toxicity
300 µM
Hemolytic
Hemolytic_activity: [Ref:15003829]HC50>300 µM against washed human erythrocytes

Target

erythrocytes

Source & Reference

NA
DRAMP
Regul. Pept 2004 118: 135-141.
Evidence 4 Hemolysis

Activity

300 µM
HC50
[Ref:15003829]HC50>300 µM against washed human erythrocytes
Hemolysis

Target

washed human erythrocytes

Source & Reference

APD_hemolytic PD_Hemolysis
Regul. Pept 2004 118: 135-141.
DRAMP4
APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_hemolytic APD hemolytic peptide annotation.