Back to search

Peptide record

TPDB07295

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB07295
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept dbAMP 3.0 i2APP APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLPLIGKVLSGIL
Physicochemical Analysis
C68H116N14O15
ARNDCEQHMTWY
L
1369.75
10.10
1
0
8
+1
-2.33
1.854
202.31
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
4
L
1
K
0
M
1
F
1
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 4 K: 1 M: 0 F: 1 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
13
C68H116N14O15
1369.75
10.10
+1
-2.33
1.854
Evidence Records 22 records
Evidence 1 Activity

Activity

MIC
Antibacterial
64 µM

Target

Escherichia coli B21

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against B. megaterium and E. coli B21 (MIC 64 uM), E.cloacae beta12 (MIC >128 uM), P.aeruginosa PA14 (MIC > 128 uM), S.epidermidis ATCC1222
Evidence 2 Activity

Activity

MIC
Antibacterial
>128 µM

Target

E.cloacae beta12

Source & Reference

dbAMP DRAMP

Other

Active against B. megaterium and E. coli B21 (MIC 64 uM), E.cloacae beta12 (MIC >128 uM), P.aeruginosa PA14 (MIC > 128 uM), S.epidermidis ATCC12228 (MIC >128 uM) ( Bosquetti et a
Evidence 3 Activity

Activity

MIC
Antibacterial
>128 µM

Target

S.epidermidis ATCC12228

Source & Reference

dbAMP DRAMP

Other

. coli B21 (MIC 64 uM), E.cloacae beta12 (MIC >128 uM), P.aeruginosa PA14 (MIC > 128 uM), S.epidermidis ATCC12228 (MIC >128 uM) ( Bosquetti et al., 2024 . Also, B. subtilis 3562 (MIC 80 ug/ml), A. oxydans 9333 (MIC ug
Evidence 4 Activity

Activity

MIC
Antibacterial
80 µg/mL

Target

B. subtilis 3562

Source & Reference

dbAMP DRAMP

Other

14 (MIC > 128 uM), S.epidermidis ATCC12228 (MIC >128 uM) ( Bosquetti et al., 2024 . Also, B. subtilis 3562 (MIC 80 ug/ml), A. oxydans 9333 (MIC ug/ml), C.albicans (MIC 320 ug/ml). Parasites: Also active against
Evidence 5 Activity

Activity

MIC
Antibacterial
320 µg/mL

Target

C.albicans

Source & Reference

dbAMP DRAMP

Other

quetti et al., 2024 . Also, B. subtilis 3562 (MIC 80 ug/ml), A. oxydans 9333 (MIC ug/ml), C.albicans (MIC 320 ug/ml). Parasites: Also active against parasites L. mexicana (Molecules. 2015 Feb 6 20(2):2775-8
Evidence 6 Activity

Activity

MIC
Antifungal
64 µM

Target

Escherichia coli B21

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against B. megaterium and E. coli B21 (MIC 64 uM), E.cloacae beta12 (MIC >128 uM), P.aeruginosa PA14 (MIC > 128 uM), S.epidermidis ATCC1222
Evidence 7 Activity

Activity

MIC
Antifungal
>128 µM

Target

E.cloacae beta12

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against B. megaterium and E. coli B21 (MIC 64 uM), E.cloacae beta12 (MIC >128 uM), P.aeruginosa PA14 (MIC > 128 uM), S.epidermidis ATCC12228 (MIC >128 uM) ( Bosquetti et a
Evidence 8 Activity

Activity

MIC
Antifungal
>128 µM

Target

S.epidermidis ATCC12228

Source & Reference

dbAMP DRAMP Antifungipept

Other

. coli B21 (MIC 64 uM), E.cloacae beta12 (MIC >128 uM), P.aeruginosa PA14 (MIC > 128 uM), S.epidermidis ATCC12228 (MIC >128 uM) ( Bosquetti et al., 2024 . Also, B. subtilis 3562 (MIC 80 ug/ml), A. oxydans 9333 (MIC ug
Evidence 9 Activity

Activity

MIC
Antifungal
80 µg/mL

Target

B. subtilis 3562

Source & Reference

dbAMP DRAMP Antifungipept

Other

14 (MIC > 128 uM), S.epidermidis ATCC12228 (MIC >128 uM) ( Bosquetti et al., 2024 . Also, B. subtilis 3562 (MIC 80 ug/ml), A. oxydans 9333 (MIC ug/ml), C.albicans (MIC 320 ug/ml). Parasites: Also active against
Evidence 10 Activity

Activity

MIC
Antifungal
320 µg/mL

Target

C.albicans

Source & Reference

dbAMP DRAMP Antifungipept

Other

quetti et al., 2024 . Also, B. subtilis 3562 (MIC 80 ug/ml), A. oxydans 9333 (MIC ug/ml), C.albicans (MIC 320 ug/ml). Parasites: Also active against parasites L. mexicana (Molecules. 2015 Feb 6 20(2):2775-8
Evidence 11 Activity

Activity

MIC
Antiparasitic
64 µM

Target

Escherichia coli B21

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
Active against B. megaterium and E. coli B21 (MIC 64 uM), E.cloacae beta12 (MIC >128 uM), P.aeruginosa PA14 (MIC > 128 uM), S.epidermidis ATCC1222
Evidence 12 Activity

Activity

MIC
Antiparasitic
>128 µM

Target

E.cloacae beta12

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against B. megaterium and E. coli B21 (MIC 64 uM), E.cloacae beta12 (MIC >128 uM), P.aeruginosa PA14 (MIC > 128 uM), S.epidermidis ATCC12228 (MIC >128 uM) ( Bosquetti et a
Evidence 13 Activity

Activity

MIC
Antiparasitic
>128 µM

Target

S.epidermidis ATCC12228

Source & Reference

dbAMP 3.0 DRAMP

Other

. coli B21 (MIC 64 uM), E.cloacae beta12 (MIC >128 uM), P.aeruginosa PA14 (MIC > 128 uM), S.epidermidis ATCC12228 (MIC >128 uM) ( Bosquetti et al., 2024 . Also, B. subtilis 3562 (MIC 80 ug/ml), A. oxydans 9333 (MIC ug
Evidence 14 Activity

Activity

MIC
Antiparasitic
80 µg/mL

Target

B. subtilis 3562

Source & Reference

dbAMP 3.0 DRAMP

Other

14 (MIC > 128 uM), S.epidermidis ATCC12228 (MIC >128 uM) ( Bosquetti et al., 2024 . Also, B. subtilis 3562 (MIC 80 ug/ml), A. oxydans 9333 (MIC ug/ml), C.albicans (MIC 320 ug/ml). Parasites: Also active against
Evidence 15 Activity

Activity

MIC
Antiparasitic
320 µg/mL

Target

C.albicans

Source & Reference

dbAMP 3.0 DRAMP

Other

quetti et al., 2024 . Also, B. subtilis 3562 (MIC 80 ug/ml), A. oxydans 9333 (MIC ug/ml), C.albicans (MIC 320 ug/ml). Parasites: Also active against parasites L. mexicana (Molecules. 2015 Feb 6 20(2):2775-8
Evidence 16 Activity

Activity

MIC
Antiviral
64 µM

Target

Escherichia coli B21

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
Active against B. megaterium and E. coli B21 (MIC 64 uM), E.cloacae beta12 (MIC >128 uM), P.aeruginosa PA14 (MIC > 128 uM), S.epidermidis ATCC1222
Evidence 17 Activity

Activity

MIC
Antiviral
>128 µM

Target

E.cloacae beta12

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against B. megaterium and E. coli B21 (MIC 64 uM), E.cloacae beta12 (MIC >128 uM), P.aeruginosa PA14 (MIC > 128 uM), S.epidermidis ATCC12228 (MIC >128 uM) ( Bosquetti et a
Evidence 18 Activity

Activity

MIC
Antiviral
>128 µM

Target

S.epidermidis ATCC12228

Source & Reference

dbAMP 3.0 DRAMP

Other

. coli B21 (MIC 64 uM), E.cloacae beta12 (MIC >128 uM), P.aeruginosa PA14 (MIC > 128 uM), S.epidermidis ATCC12228 (MIC >128 uM) ( Bosquetti et al., 2024 . Also, B. subtilis 3562 (MIC 80 ug/ml), A. oxydans 9333 (MIC ug
Evidence 19 Activity

Activity

MIC
Antiviral
80 µg/mL

Target

B. subtilis 3562

Source & Reference

dbAMP 3.0 DRAMP

Other

14 (MIC > 128 uM), S.epidermidis ATCC12228 (MIC >128 uM) ( Bosquetti et al., 2024 . Also, B. subtilis 3562 (MIC 80 ug/ml), A. oxydans 9333 (MIC ug/ml), C.albicans (MIC 320 ug/ml). Parasites: Also active against
Evidence 20 Activity

Activity

MIC
Antiviral
320 µg/mL

Target

C.albicans

Source & Reference

dbAMP 3.0 DRAMP

Other

quetti et al., 2024 . Also, B. subtilis 3562 (MIC 80 ug/ml), A. oxydans 9333 (MIC ug/ml), C.albicans (MIC 320 ug/ml). Parasites: Also active against parasites L. mexicana (Molecules. 2015 Feb 6 20(2):2775-8
Evidence 21 Activity

Activity

12% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
12% Hemolysis | 64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Anti-Pseudomonas activity of frog skin antimicrobial peptides in a Caenorhabditis elegans infection model: a plausible mode of action in vitro and in vivo. | Antimicrob Agents Chemother | 2010
Evidence 22 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.