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Peptide record

TPDB07281

Antibacterial Antifungal Antiviral Toxicity standard

13 amino acids

3D PDB MODEL

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TPDB ID TPDB07281

Activity

Antibacterial Antifungal Antiviral Toxicity

Activity_category_statistics

Anti-infective peptides Toxicity and safety peptides

Database_Source

AntiBP3 Peptipedia Antifp Antifungipept AI4AVP dbAMP 3.0 ToxinPred 3.0

Sequence_Type

standard

Has_Modification No

Description A 13-aa standard natural multi-activity (Antibacterial, Antifungal, Antiviral, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifp, and other sources, with an available 3D structural model.

Sequence

ILGEIWKGIKDIL

FASTA

>TPDB07281|Antibacterial;Antifungal;Antiviral;Toxicity|length=13
ILGEIWKGIKDIL

Formula C72H120N16O18

Absent Amino Acids ARNCQHMFPSTYV

Common Amino Acids I

Mass 1497.84

PI 6.99

Basic Residues 2

Acidic Residues 2

Hydrophobic Residues 7

Net Charge -0

Boman Index 1.04

Hydrophobicity 0.700

Aliphatic Index 180.00

Half Life

Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour

Extinction Coefficient Cystines 5500

Absorbance 280nm 367.20

Polar Residues 0

number

Amino Acid Distribution

A: 0 R: 0 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 2 H: 0 I: 4 L: 2 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0

Length

Formula

C72H120N16O18

Mass

1497.84

6.99

Net Charge

-0

Boman Index

1.04

Hydrophobicity

0.700

Evidence 1 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 41 µM

Target

Target Organism B. megaterium AB 90008

Source & Reference

Database Source NA

Other

Evidence Text

Active against Gram+ S-aureus AB 94004 (MIC>82 uM), B. megaterium AB 90008 (MIC 41 uM) M. luteus AB2010179 (MIC 82 uM) Gram- P-putida PP (MIC > 82 uM), P-fluorences PF (MIC>

Evidence 2 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 82 µM

Target

Target Organism M. luteus AB2010179

Source & Reference

Database Source NA

Other

Evidence Text

Active against Gram+ S-aureus AB 94004 (MIC>82 uM), B. megaterium AB 90008 (MIC 41 uM) M. luteus AB2010179 (MIC 82 uM) Gram- P-putida PP (MIC > 82 uM), P-fluorences PF (MIC> 82 uM), S-enterica AB 2010185 (MI

Evidence 3 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 82 µM

Target

Target Organism Escherichia coli DH5alpha

Source & Reference

Database Source NA

Other

Evidence Text

putida PP (MIC > 82 uM), P-fluorences PF (MIC> 82 uM), S-enterica AB 2010185 (MIC>82 uM), E. coli DH5alpha (MIC 82 uM), and E-cloacae AB 2010162 (MIC> 83 uM).

Evidence 4 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 41 µM

Target

Target Organism B. megaterium AB 90008

Source & Reference

Database Source Antifungipept

Other

Evidence Text

Active against Gram+ S-aureus AB 94004 (MIC>82 uM), B. megaterium AB 90008 (MIC 41 uM) M. luteus AB2010179 (MIC 82 uM) Gram- P-putida PP (MIC > 82 uM), P-fluorences PF (MIC>

Evidence 5 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 82 µM

Target

Target Organism M. luteus AB2010179

Source & Reference

Database Source Antifungipept

Other

Evidence Text

Evidence 6 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 82 µM

Target

Target Organism Escherichia coli DH5alpha

Source & Reference

Database Source Antifungipept

Other

Evidence Text

putida PP (MIC > 82 uM), P-fluorences PF (MIC> 82 uM), S-enterica AB 2010185 (MIC>82 uM), E. coli DH5alpha (MIC 82 uM), and E-cloacae AB 2010162 (MIC> 83 uM).

Evidence 7 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 41 µM

Target

Target Organism B. megaterium AB 90008

Source & Reference

Database Source dbAMP 3.0

Other

Source Activity Label	Source Definition
Antiviral	dbAMP 3.0 classified under the Anti-viral function class.

Evidence Text

Active against Gram+ S-aureus AB 94004 (MIC>82 uM), B. megaterium AB 90008 (MIC 41 uM) M. luteus AB2010179 (MIC 82 uM) Gram- P-putida PP (MIC > 82 uM), P-fluorences PF (MIC>

Evidence 8 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 82 µM

Target

Target Organism M. luteus AB2010179

Source & Reference

Database Source dbAMP 3.0

Other

Evidence Text

Evidence 9 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 82 µM

Target

Target Organism Escherichia coli DH5alpha

Source & Reference

Database Source dbAMP 3.0

Other

Evidence Text

putida PP (MIC > 82 uM), P-fluorences PF (MIC> 82 uM), S-enterica AB 2010185 (MIC>82 uM), E. coli DH5alpha (MIC 82 uM), and E-cloacae AB 2010162 (MIC> 83 uM).

Evidence 10 Activity

Activity

Activity Endpoint 0% Hemolysis

Detail Source Activity Toxicity

Activity Measurement 48 µM

Toxicity Type Hemolytic Cytotoxic

Toxicity Raw

0% Hemolysis | 48 | µM | target cell: Human erythrocytes

Target

Target Cell Human erythrocytes

Source & Reference

Database Source NA

Source Database DBAASP

Reference

Genomic and functional characterization of three new venom peptides from the scorpion Heterometrus spinifer. | Peptides | 2014

Evidence 11 Activity

Activity

Activity Endpoint 0% Hemolysis

Detail Source Activity Toxicity

Activity Measurement 100 µM

Toxicity Type Hemolytic Cytotoxic

Toxicity Raw

0% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Target Cell Human erythrocytes

Source & Reference

Database Source NA

Source Database DBAASP

Reference

Augmentation of Antimicrobial Activity of Spiniferin by Introducing an Arginine Residue Toward Its Amino Terminus: A Possible Role of Cation-π Interaction | ACS Bio Med Chem Au | 2025