Back to search

Peptide record

TPDB07274

Antibacterial Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB07274
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLPVIAGVLSKLF
Physicochemical Analysis
C71H114N14O15
RNDCEQHMTWY
L
1403.77
10.10
1
0
9
+1
-2.70
1.923
172.31
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
3
L
1
K
0
M
2
F
1
P
1
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 3 K: 1 M: 0 F: 2 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
13
C71H114N14O15
1403.77
10.10
+1
-2.70
1.923
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
10 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against S. aureus (MIC 10 uM) and E. coli (MIC 40 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
40 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus (MIC 10 uM) and E. coli (MIC 40 uM).
Evidence 3 Activity

Activity

MIC
Antifungal
10 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against S. aureus (MIC 10 uM) and E. coli (MIC 40 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
40 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against S. aureus (MIC 10 uM) and E. coli (MIC 40 uM).
Evidence 5 Activity

Activity

0% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
0% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and bioactivity evaluation of two novel temporins from the skin secretion of the European edible frog, Pelophylax kl. esculentus. | Biochem Biophys Res Commun | 2016
Evidence 6 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.27255993]Non-hemolytic activity at 10 µM

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochem Biophys Res Commun. 2016 Aug 5 476(4):566-73.