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Peptide record

TPDB07269

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07269
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
PKLLETFLSKWIG
Physicochemical Analysis
C75H118N16O18
ARNDCQHMYV
L
1531.86
9.88
2
1
6
+1
-0.24
0.231
120.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
5500
359.04
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
0
Q
1
G
0
H
1
I
3
L
2
K
0
M
1
F
1
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 1 L: 3 K: 2 M: 0 F: 1 P: 1 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C75H118N16O18
1531.86
9.88
+1
-0.24
0.231
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
9 µM
Hemolytic Cytotoxic
10% Hemolysis | 9 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Change of glutamic acid to lysine in a 13-residue antibacterial and hemolytic peptide results in enhanced antibacterial activity without increase in hemolytic activity. | Antimicrob Agents Chemother | 1992
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis