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Peptide record

TPDB07265

Antibacterial Antifungal Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07265
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb APD_complete PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLSTIWNGIKGLL
Physicochemical Analysis
C71H112N16O17
ARDCEQHMPYV
L
1461.77
10.10
1
0
7
+1
-3.58
0.969
150.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
376.26
3
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
3
L
1
K
0
M
1
F
0
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 3 K: 1 M: 0 F: 1 P: 0 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C71H112N16O17
1461.77
10.10
+1
-3.58
0.969
Evidence Records 6 records
Evidence 1 Activity

Activity

EC50
Toxicity
51.95 µM
Cytotoxic
EC50 | 51.95 | µM | target cell: Baby Hamster Kidney cells BHK-21

Target

Baby Hamster Kidney cells BHK-21

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
35.85 µM
Hemolytic Cytotoxic
10% Hemolysis | 35.85 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
155.6 µM
Hemolytic Cytotoxic
50% Hemolysis | 155.6 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 4 Activity

Activity

90% Hemolysis
Toxicity
675.22 µM
Hemolytic Cytotoxic
90% Hemolysis | 675.22 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 5 Activity

Activity

<5% Hemolysis
Toxicity
380 µM
Hemolytic Cytotoxic
<5% Hemolysis | 380 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structural Characterization of Scorpion Peptides and Their Bactericidal Activity Against Clinical Isolates of Multidrug-Resistant Bacteria. | PLoS One | 2019
Evidence 6 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.