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Peptide record

TPDB07263

Antibacterial Antifungal Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07263
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP APD_complete APD_hemolytic PD_Hemolysis ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
FITGLISGLMKAL
Physicochemical Analysis
C64H110N14O16S1
RNDCEQHPWYV
L
1363.72
10.10
1
0
8
+1
-2.55
1.592
157.69
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
3
L
1
K
1
M
1
F
0
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 3 K: 1 M: 1 F: 1 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C64H110N14O16S1
1363.72
10.10
+1
-2.55
1.592
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (IS) (MIC >400 uM), E. faecalis 981 (IS) (MIC 25 uM), N. asteroides 201
Evidence 2 Activity

Activity

MIC
Antibacterial
>400 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP

Other

C >400 uM), K.Pneumoniae 08040724 (IS) (MIC >400 uM), E.cloacae CGMCC 1.57 (MIC >400 uM), E.coli ATCC 25922 (MIC >400 uM), P.faecalis X29 (IS) (MIC 200 uM), C. glabrata 090902 (IS) (MIC 100 uM), C.albicans ATCC1
Evidence 3 Activity

Activity

MIC
Antibacterial
>400 µM

Target

C.albicans ATCC10231

Source & Reference

dbAMP

Other

22 (MIC >400 uM), P.faecalis X29 (IS) (MIC 200 uM), C. glabrata 090902 (IS) (MIC 100 uM), C.albicans ATCC10231 (MIC>400 uM). IS= Isolated strain.
Evidence 4 Activity

Activity

MIC
Antifungal
12.5 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (IS) (MIC >400 uM), E. faecalis 981 (IS) (MIC 25 uM), N. asteroides 201
Evidence 5 Activity

Activity

MIC
Antifungal
>400 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

C >400 uM), K.Pneumoniae 08040724 (IS) (MIC >400 uM), E.cloacae CGMCC 1.57 (MIC >400 uM), E.coli ATCC 25922 (MIC >400 uM), P.faecalis X29 (IS) (MIC 200 uM), C. glabrata 090902 (IS) (MIC 100 uM), C.albicans ATCC1
Evidence 6 Activity

Activity

MIC
Antifungal
>400 µM

Target

C.albicans ATCC10231

Source & Reference

dbAMP CAFPdb Antifungipept

Other

22 (MIC >400 uM), P.faecalis X29 (IS) (MIC 200 uM), C. glabrata 090902 (IS) (MIC 100 uM), C.albicans ATCC10231 (MIC>400 uM). IS= Isolated strain.
Evidence 7 Activity

Activity

11% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
11% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple antimicrobial peptides from the skin of fine-spined frog, Hylarana spinulosa (Ranidae). | Biochimie | 2013
Evidence 8 Activity

Activity

52% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
52% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple antimicrobial peptides from the skin of fine-spined frog, Hylarana spinulosa (Ranidae). | Biochimie | 2013
Evidence 9 Hemolysis

Source & Reference

APD_complete APD_hemolytic PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.