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Peptide record

TPDB07259

Antibacterial Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB07259
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
INLKAIAALARNY
Physicochemical Analysis
C65H111N19O17
DCEQGHMFPSTWV
A
1430.71
10.42
2
0
9
+2
-0.72
0.546
150.77
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
1490
104.14
3
Residue Composition
number
4
A
1
R
2
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
2
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 4 R: 1 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 2 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
13
C65H111N19O17
1430.71
10.42
+2
-0.72
0.546
Evidence Records 23 records
Evidence 1 Activity

Activity

MIC
Antibacterial
10 µM

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram-positive S. aureus ATCC25923 (MIC 10 uM), E. faecalis ATCC29212 (MIC 5 uM), S. aureus IS 10# (MIC 40 uM), S. aureus IS 37# (MIC 10
Evidence 2 Activity

Activity

MIC
Antibacterial
5 µM

Target

Enterococcus faecalis ATCC29212

Source & Reference

dbAMP

Other

Active against Gram-positive S. aureus ATCC25923 (MIC 10 uM), E. faecalis ATCC29212 (MIC 5 uM), S. aureus IS 10# (MIC 40 uM), S. aureus IS 37# (MIC 10 uM), Gram-negative E.coli ATCC259
Evidence 3 Activity

Activity

MIC
Antibacterial
>160 µM

Target

E.coli ATCC25922

Source & Reference

dbAMP

Other

212 (MIC 5 uM), S. aureus IS 10# (MIC 40 uM), S. aureus IS 37# (MIC 10 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E.cloacae ATCC13047 (MIC >160 uM), K. pneumoniae ATCC700603 (MIC 80 uM), B. pyocyaneus C
Evidence 4 Activity

Activity

MIC
Antibacterial
>160 µM

Target

E.cloacae ATCC13047

Source & Reference

dbAMP

Other

(MIC 40 uM), S. aureus IS 37# (MIC 10 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E.cloacae ATCC13047 (MIC >160 uM), K. pneumoniae ATCC700603 (MIC 80 uM), B. pyocyaneus CMCCB1010 (MIC 80 uM), P. aeruginosa
Evidence 5 Activity

Activity

MIC
Antibacterial
80 µM

Target

Klebsiella pneumoniae ATCC700603

Source & Reference

dbAMP

Other

10 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E.cloacae ATCC13047 (MIC >160 uM), K. pneumoniae ATCC700603 (MIC 80 uM), B. pyocyaneus CMCCB1010 (MIC 80 uM), P. aeruginosa ATCC27853 (MIC 80 uM), B.dysenteriae
Evidence 6 Activity

Activity

MIC
Antibacterial
80 µM

Target

B. pyocyaneus CMCCB1010

Source & Reference

dbAMP

Other

2 (MIC >160 uM), E.cloacae ATCC13047 (MIC >160 uM), K. pneumoniae ATCC700603 (MIC 80 uM), B. pyocyaneus CMCCB1010 (MIC 80 uM), P. aeruginosa ATCC27853 (MIC 80 uM), B.dysenteriae (MIC >160 uM), E. coli IS 37# (MIC 80
Evidence 7 Activity

Activity

MIC
Antibacterial
80 µM

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP

Other

(MIC >160 uM), K. pneumoniae ATCC700603 (MIC 80 uM), B. pyocyaneus CMCCB1010 (MIC 80 uM), P. aeruginosa ATCC27853 (MIC 80 uM), B.dysenteriae (MIC >160 uM), E. coli IS 37# (MIC 80 uM), E. coli IS 117# (MIC 40 uM), E.
Evidence 8 Activity

Activity

MIC
Antibacterial
>160 µM

Target

B.dysenteriae

Source & Reference

dbAMP

Other

03 (MIC 80 uM), B. pyocyaneus CMCCB1010 (MIC 80 uM), P. aeruginosa ATCC27853 (MIC 80 uM), B.dysenteriae (MIC >160 uM), E. coli IS 37# (MIC 80 uM), E. coli IS 117# (MIC 40 uM), E. coli IS 218# (MIC 40 uM), P.
Evidence 9 Activity

Activity

MIC
Antibacterial
80 µM

Target

Candida albicans ATCC2002

Source & Reference

dbAMP

Other

(MIC 40 uM), P. aeruginosa IS 350# (MIC 10 uM), K.pneumoniae IS 59# (MIC >160 uM), fungi C. albicans ATCC2002 (MIC 80 uM), C. albicans ATCC90028 (MIC 20 uM), and C.parapsilosis ATCC22019 (MIC >160 uM). Updated 7
Evidence 10 Activity

Activity

MIC
Antibacterial
20 µM

Target

Candida albicans ATCC90028

Source & Reference

dbAMP

Other

# (MIC 10 uM), K.pneumoniae IS 59# (MIC >160 uM), fungi C. albicans ATCC2002 (MIC 80 uM), C. albicans ATCC90028 (MIC 20 uM), and C.parapsilosis ATCC22019 (MIC >160 uM). Updated 7/2021
Evidence 11 Activity

Activity

MIC
Antibacterial
>160 µM

Target

C.parapsilosis ATCC22019

Source & Reference

dbAMP

Other

>160 uM), fungi C. albicans ATCC2002 (MIC 80 uM), C. albicans ATCC90028 (MIC 20 uM), and C.parapsilosis ATCC22019 (MIC >160 uM). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antifungal
10 µM

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram-positive S. aureus ATCC25923 (MIC 10 uM), E. faecalis ATCC29212 (MIC 5 uM), S. aureus IS 10# (MIC 40 uM), S. aureus IS 37# (MIC 10
Evidence 13 Activity

Activity

MIC
Antifungal
5 µM

Target

Enterococcus faecalis ATCC29212

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram-positive S. aureus ATCC25923 (MIC 10 uM), E. faecalis ATCC29212 (MIC 5 uM), S. aureus IS 10# (MIC 40 uM), S. aureus IS 37# (MIC 10 uM), Gram-negative E.coli ATCC259
Evidence 14 Activity

Activity

MIC
Antifungal
>160 µM

Target

E.coli ATCC25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

212 (MIC 5 uM), S. aureus IS 10# (MIC 40 uM), S. aureus IS 37# (MIC 10 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E.cloacae ATCC13047 (MIC >160 uM), K. pneumoniae ATCC700603 (MIC 80 uM), B. pyocyaneus C
Evidence 15 Activity

Activity

MIC
Antifungal
>160 µM

Target

E.cloacae ATCC13047

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 40 uM), S. aureus IS 37# (MIC 10 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E.cloacae ATCC13047 (MIC >160 uM), K. pneumoniae ATCC700603 (MIC 80 uM), B. pyocyaneus CMCCB1010 (MIC 80 uM), P. aeruginosa
Evidence 16 Activity

Activity

MIC
Antifungal
80 µM

Target

Klebsiella pneumoniae ATCC700603

Source & Reference

dbAMP CAFPdb Antifungipept

Other

10 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E.cloacae ATCC13047 (MIC >160 uM), K. pneumoniae ATCC700603 (MIC 80 uM), B. pyocyaneus CMCCB1010 (MIC 80 uM), P. aeruginosa ATCC27853 (MIC 80 uM), B.dysenteriae
Evidence 17 Activity

Activity

MIC
Antifungal
80 µM

Target

B. pyocyaneus CMCCB1010

Source & Reference

dbAMP CAFPdb Antifungipept

Other

2 (MIC >160 uM), E.cloacae ATCC13047 (MIC >160 uM), K. pneumoniae ATCC700603 (MIC 80 uM), B. pyocyaneus CMCCB1010 (MIC 80 uM), P. aeruginosa ATCC27853 (MIC 80 uM), B.dysenteriae (MIC >160 uM), E. coli IS 37# (MIC 80
Evidence 18 Activity

Activity

MIC
Antifungal
80 µM

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC >160 uM), K. pneumoniae ATCC700603 (MIC 80 uM), B. pyocyaneus CMCCB1010 (MIC 80 uM), P. aeruginosa ATCC27853 (MIC 80 uM), B.dysenteriae (MIC >160 uM), E. coli IS 37# (MIC 80 uM), E. coli IS 117# (MIC 40 uM), E.
Evidence 19 Activity

Activity

MIC
Antifungal
>160 µM

Target

B.dysenteriae

Source & Reference

dbAMP CAFPdb Antifungipept

Other

03 (MIC 80 uM), B. pyocyaneus CMCCB1010 (MIC 80 uM), P. aeruginosa ATCC27853 (MIC 80 uM), B.dysenteriae (MIC >160 uM), E. coli IS 37# (MIC 80 uM), E. coli IS 117# (MIC 40 uM), E. coli IS 218# (MIC 40 uM), P.
Evidence 20 Activity

Activity

MIC
Antifungal
80 µM

Target

Candida albicans ATCC2002

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 40 uM), P. aeruginosa IS 350# (MIC 10 uM), K.pneumoniae IS 59# (MIC >160 uM), fungi C. albicans ATCC2002 (MIC 80 uM), C. albicans ATCC90028 (MIC 20 uM), and C.parapsilosis ATCC22019 (MIC >160 uM). Updated 7
Evidence 21 Activity

Activity

MIC
Antifungal
20 µM

Target

Candida albicans ATCC90028

Source & Reference

dbAMP CAFPdb Antifungipept

Other

# (MIC 10 uM), K.pneumoniae IS 59# (MIC >160 uM), fungi C. albicans ATCC2002 (MIC 80 uM), C. albicans ATCC90028 (MIC 20 uM), and C.parapsilosis ATCC22019 (MIC >160 uM). Updated 7/2021
Evidence 22 Activity

Activity

MIC
Antifungal
>160 µM

Target

C.parapsilosis ATCC22019

Source & Reference

dbAMP CAFPdb Antifungipept

Other

>160 uM), fungi C. albicans ATCC2002 (MIC 80 uM), C. albicans ATCC90028 (MIC 20 uM), and C.parapsilosis ATCC22019 (MIC >160 uM). Updated 7/2021
Evidence 23 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptides from the venom gland of the social wasp Vespa tropica. | Toxicon | 2013