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Peptide record

TPDB07255

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07255
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ILPILAPLIGGLL
Physicochemical Analysis
C65H115N13O14
RNDCEQHKMFSTWYV
L
1302.71
6.02
0
0
9
-0
-2.98
2.331
247.69
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
3
I
5
L
0
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 5 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C65H115N13O14
1302.71
6.02
-0
-2.98
2.331
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>450 µM
Hemolytic Cytotoxic
50% Hemolysis | >450 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and characterisation of a novel antimicrobial polypeptide from the skin secretion of a Chinese frog (Rana chensinensis). | Int J Antimicrob Agents | 2009
Evidence 2 Activity

Activity

HC50
Toxicity
180 µM
Hemolytic
Hemolytic_activity: [Ref:19539775]HC50=180 µM against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Comp Biochem Physiol B Biochem Mol Biol. 2009 Oct 154(2):174-178.