Back to search

Peptide record

TPDB07252

Antibacterial Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB07252
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FFPIVGKRLYGLL
Physicochemical Analysis
C77H119N17O15
ANDCEQHMSTW
L
1522.90
10.42
2
0
8
+2
-2.85
1.046
142.31
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
1490
97.84
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
1
I
3
L
1
K
0
M
2
F
1
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 3 K: 1 M: 0 F: 2 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
13
C77H119N17O15
1522.90
10.42
+2
-2.85
1.046
Evidence Records 14 records
Evidence 1 Activity

Activity

MIC
Antibacterial
70 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli ATCC 25922 (MIC 70 ug/ml), B. dysenteriae (MIC 18.75 ug/ml), S. aureus ATCC 2592 (MIC 4.7 ug/ml), B. subtilis ATCC
Evidence 2 Activity

Activity

MIC
Antibacterial
18.75 µg/mL

Target

B. dysenteriae

Source & Reference

dbAMP DRAMP

Other

Active against E. coli ATCC 25922 (MIC 70 ug/ml), B. dysenteriae (MIC 18.75 ug/ml), S. aureus ATCC 2592 (MIC 4.7 ug/ml), B. subtilis ATCC 6633 (MIC 9.38 ug/ml), and fungi C
Evidence 3 Activity

Activity

MIC
Antibacterial
4.7 µg/mL

Target

Staphylococcus aureus ATCC 2592

Source & Reference

dbAMP DRAMP

Other

Active against E. coli ATCC 25922 (MIC 70 ug/ml), B. dysenteriae (MIC 18.75 ug/ml), S. aureus ATCC 2592 (MIC 4.7 ug/ml), B. subtilis ATCC 6633 (MIC 9.38 ug/ml), and fungi C. albicans ATCC 2002 (MIC 37.5 ug/ml)
Evidence 4 Activity

Activity

MIC
Antibacterial
9.38 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP DRAMP

Other

22 (MIC 70 ug/ml), B. dysenteriae (MIC 18.75 ug/ml), S. aureus ATCC 2592 (MIC 4.7 ug/ml), B. subtilis ATCC 6633 (MIC 9.38 ug/ml), and fungi C. albicans ATCC 2002 (MIC 37.5 ug/ml).
Evidence 5 Activity

Activity

MIC
Antibacterial
37.5 µg/mL

Target

Candida albicans ATCC 2002

Source & Reference

dbAMP DRAMP

Other

), S. aureus ATCC 2592 (MIC 4.7 ug/ml), B. subtilis ATCC 6633 (MIC 9.38 ug/ml), and fungi C. albicans ATCC 2002 (MIC 37.5 ug/ml).
Evidence 6 Activity

Activity

MIC
Antifungal
70 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli ATCC 25922 (MIC 70 ug/ml), B. dysenteriae (MIC 18.75 ug/ml), S. aureus ATCC 2592 (MIC 4.7 ug/ml), B. subtilis ATCC
Evidence 7 Activity

Activity

MIC
Antifungal
18.75 µg/mL

Target

B. dysenteriae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC 25922 (MIC 70 ug/ml), B. dysenteriae (MIC 18.75 ug/ml), S. aureus ATCC 2592 (MIC 4.7 ug/ml), B. subtilis ATCC 6633 (MIC 9.38 ug/ml), and fungi C
Evidence 8 Activity

Activity

MIC
Antifungal
4.7 µg/mL

Target

Staphylococcus aureus ATCC 2592

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC 25922 (MIC 70 ug/ml), B. dysenteriae (MIC 18.75 ug/ml), S. aureus ATCC 2592 (MIC 4.7 ug/ml), B. subtilis ATCC 6633 (MIC 9.38 ug/ml), and fungi C. albicans ATCC 2002 (MIC 37.5 ug/ml)
Evidence 9 Activity

Activity

MIC
Antifungal
9.38 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

22 (MIC 70 ug/ml), B. dysenteriae (MIC 18.75 ug/ml), S. aureus ATCC 2592 (MIC 4.7 ug/ml), B. subtilis ATCC 6633 (MIC 9.38 ug/ml), and fungi C. albicans ATCC 2002 (MIC 37.5 ug/ml).
Evidence 10 Activity

Activity

MIC
Antifungal
37.5 µg/mL

Target

Candida albicans ATCC 2002

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

), S. aureus ATCC 2592 (MIC 4.7 ug/ml), B. subtilis ATCC 6633 (MIC 9.38 ug/ml), and fungi C. albicans ATCC 2002 (MIC 37.5 ug/ml).
Evidence 11 Activity

Activity

2% Hemolysis
Toxicity
25 µg/mL
Hemolytic Cytotoxic
2% Hemolysis | 25 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptide diversity in the skin of the torrent frog, Amolops jingdongensis. | Amino Acids | 2013
Evidence 12 Activity

Activity

5% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 50 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptide diversity in the skin of the torrent frog, Amolops jingdongensis. | Amino Acids | 2013
Evidence 13 Activity

Activity

8% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
8% Hemolysis | 100 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptide diversity in the skin of the torrent frog, Amolops jingdongensis. | Amino Acids | 2013
Evidence 14 Activity

Activity

% Hemolysis
Toxicity
1.79 %
Hemolytic
Hemolytic_activity: [Ref.22828809] 1.79% hemolysis at 25µg/ml, 5.22% hemolysis at 50µg/ml, 7.92% hemolysis at 100µg/ml, 10.85% hemolysis at 200µg/ml against rabbit red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Amino Acids. 2012 Jul 25.