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Peptide record

TPDB07250

Antibacterial Antifungal Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07250
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP APD_complete APD_hemolytic Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FLAGLIGGLAKML
Physicochemical Analysis
C62H106N14O14S1
RNDCEQHPSTWYV
L
1303.67
10.10
1
0
9
+1
-3.23
1.762
165.38
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
1
I
4
L
1
K
1
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 4 K: 1 M: 1 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C62H106N14O14S1
1303.67
10.10
+1
-3.23
1.762
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
9.5 µM

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus ATCC2592 (MIC 9.5 uM), B. licheniformis X39 (IS) (MIC 19 uM), S. carnosus KHS (IS) (MIC 9.5 uM), R. rhodochrous
Evidence 2 Activity

Activity

MIC
Antifungal
9.5 µM

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus ATCC2592 (MIC 9.5 uM), B. licheniformis X39 (IS) (MIC 19 uM), S. carnosus KHS (IS) (MIC 9.5 uM), R. rhodochrous
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
40 µM
Hemolytic Cytotoxic
50% Hemolysis | 40 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Molecular cloning and characterization of antimicrobial peptides from skin of the broad-folded frog, Hylarana latouchii. | Biochimie | 2012
Evidence 4 Hemolysis

Source & Reference

APD_complete APD_hemolytic PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.