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Peptide record

TPDB07242

Antibacterial Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07242
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
VRRYPWWWPYLRR
Physicochemical Analysis
C96H132N28O16
ANDCEQGHIKMFST
R
1934.28
11.94
4
0
7
+4
-3.78
-1.423
52.31
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
19480
1007.09
2
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
2
P
0
S
0
T
3
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 3 Y: 2 V: 1
Chemical Descriptors
13
C96H132N28O16
1934.28
11.94
+4
-3.78
-1.423
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
220 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 220 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function analysis of tritrpticin analogs: potential relationships between antimicrobial activities, model membrane interactions, and their micelle-bound NMR structures. | Biophys J | 2006
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis