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Peptide record

TPDB07227

Antibacterial Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07227
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
PKLLKTFLSKWIG
Physicochemical Analysis
C76H123N17O16
ARNDCEQHMYV
LK
1530.92
10.84
3
0
6
+3
-1.27
0.200
120.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
5500
359.26
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
3
L
3
K
0
M
1
F
1
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 3 K: 3 M: 0 F: 1 P: 1 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C76H123N17O16
1530.92
10.84
+3
-1.27
0.200
Evidence Records 2 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
30 µg/mL
Hemolytic Cytotoxic
100% Hemolysis | 30 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Biological activities of retro and diastereo analogs of a 13-residue peptide with antimicrobial and hemolytic activities. | J Pept Res | 2001
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis