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Peptide record

TPDB07225

Antibacterial Antifungal Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07225
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
LLQWLSKLLGRWL
Physicochemical Analysis
C80H128N20O16
ANDCEHIMFPTYV
L
1626.02
11.49
2
0
8
+2
-4.54
0.608
180.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
11000
676.50
2
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
0
I
6
L
1
K
0
M
0
F
0
P
1
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 6 K: 1 M: 0 F: 0 P: 0 S: 1 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
13
C80H128N20O16
1626.02
11.49
+2
-4.54
0.608
Evidence Records 5 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
12 µM
Hemolytic Cytotoxic
100% Hemolysis | 12 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship, conformational and biological studies of temporin L analogues. | J Med Chem | 2011
Evidence 2 Activity

Activity

78% Hemolysis
Toxicity
6 µM
Hemolytic Cytotoxic
78% Hemolysis | 6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship, conformational and biological studies of temporin L analogues. | J Med Chem | 2011
Evidence 3 Activity

Activity

13% Hemolysis
Toxicity
3 µM
Hemolytic Cytotoxic
13% Hemolysis | 3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship, conformational and biological studies of temporin L analogues. | J Med Chem | 2011
Evidence 4 Activity

Activity

8% Hemolysis
Toxicity
1.5 µM
Hemolytic Cytotoxic
8% Hemolysis | 1.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship, conformational and biological studies of temporin L analogues. | J Med Chem | 2011
Evidence 5 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis