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Peptide record

TPDB07221

M3 Antibacterial Antifungal Cell-penetrating Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07221
M3
Antibacterial Antifungal Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP CellPPD CellPPD-MOD CPPsite3.0 PerseuCPP
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, and Cell-penetrating Peptides) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with fluorescein
Sequence
KCFQWQRNMRKVR-NH2
Physicochemical Analysis
C77H126N28O17S2
ADEGHILPSTY
R
1780.14
12.13
5
0
4
+5
2.61
-1.638
22.31
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
308.96
4
Residue Composition
number
0
A
3
R
1
N
0
D
1
C
0
E
2
Q
0
G
0
H
0
I
0
L
2
K
1
M
1
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 1 E: 0 Q: 2 G: 0 H: 0 I: 0 L: 0 K: 2 M: 1 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
13
C77H126N28O17S2
1780.14
12.13
+5
2.61
-1.638
Amidation
L
Linear
Conjugation with fluorescein
N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC)C(=O)N[C@@H](CCCN=C)C(=O)O.C
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Fluorophore (fluorescein)
Vesicles at low concentartion and cytoplasm and nucleus at high concentart
Lower than hLF peptide
In vitro
CCCSTTTTSSSCC
Additional Detail Fields 1 fields
CCCSTTTTSSSCC