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Peptide record

TPDB07201

Antibacterial Antiviral Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07201
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AI4AVP, and other sources, with an available 3D structural model.
Sequence
GWFDVVKHIAKRF
Physicochemical Analysis
C78H115N21O16
NCEQLMPSTY
KFV
1602.90
10.59
4
1
7
+2
0.54
0.000
82.31
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
343.13
0
Residue Composition
number
1
A
1
R
0
N
1
D
0
C
0
E
0
Q
1
G
1
H
1
I
0
L
2
K
0
M
2
F
0
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 0 K: 2 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
13
C78H115N21O16
1602.90
10.59
+2
0.54
0.000
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
50 µM

Target

Staphylococcus aureus USA300 MRSA

Source & Reference

NA

Other

active against S. aureus USA300 MRSA (MIC 50 uM) and E. coli (MIC 12.5 uM). inhibited Human Immunodeficiency Virus Type 1 HIV-1 (EC50 2.99
Evidence 2 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

Escherichia coli

Source & Reference

NA

Other

active against S. aureus USA300 MRSA (MIC 50 uM) and E. coli (MIC 12.5 uM). inhibited Human Immunodeficiency Virus Type 1 HIV-1 (EC50 2.99 uM).
Evidence 3 Activity

Activity

MIC
Antiviral
50 µM

Target

Staphylococcus aureus USA300 MRSA

Source & Reference

dbAMP 3.0 DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
active against S. aureus USA300 MRSA (MIC 50 uM) and E. coli (MIC 12.5 uM). inhibited Human Immunodeficiency Virus Type 1 HIV-1 (EC50 2.99
Evidence 4 Activity

Activity

MIC
Antiviral
12.5 µM

Target

Escherichia coli

Source & Reference

dbAMP 3.0 DRAVP 2.0

Other

active against S. aureus USA300 MRSA (MIC 50 uM) and E. coli (MIC 12.5 uM). inhibited Human Immunodeficiency Virus Type 1 HIV-1 (EC50 2.99 uM).
Evidence 5 Activity

Activity

50% Cell death
Toxicity
10.6 µM
Cytotoxic
50% Cell death | 10.6 | µM | target cell: CEM-SS cells

Target

CEM-SS cells

Source & Reference

NA
DBAASP
Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database. | Antimicrob Agents Chemother | 2010