Back to search

Peptide record

TPDB07196

Antibacterial Antifungal Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB07196
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FLPLLAGLAAKWF
Physicochemical Analysis
C75H111N15O14
RNDCEQHIMSTYV
L
1446.80
10.10
1
0
10
+1
-5.41
1.492
143.08
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
380.15
0
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
4
L
1
K
0
M
2
F
1
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 4 K: 1 M: 0 F: 2 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C75H111N15O14
1446.80
10.10
+1
-5.41
1.492
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
18.8 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus ATCC 25923, E. faecalis 981 (MIC 18.8 uM), N. asteroides 201118 (MIC 2.3 uM), P.aeruginosa CGMCC 1.50 (inactive), K.pneumoniae 0804
Evidence 2 Activity

Activity

MIC
Antibacterial
2.3 µM

Target

N. asteroides 201118

Source & Reference

dbAMP

Other

Active against S. aureus ATCC 25923, E. faecalis 981 (MIC 18.8 uM), N. asteroides 201118 (MIC 2.3 uM), P.aeruginosa CGMCC 1.50 (inactive), K.pneumoniae 08040724 (inactive), E.coli ATCC 25922
Evidence 3 Activity

Activity

MIC
Antibacterial
150 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP

Other

01118 (MIC 2.3 uM), P.aeruginosa CGMCC 1.50 (inactive), K.pneumoniae 08040724 (inactive), E.coli ATCC 25922 (MIC 150 uM), C.albicans ATCC 10231 (inactive), and C.glabrata 090902 (inactive). Updated 7/2021 4/20
Evidence 4 Activity

Activity

MIC
Antifungal
18.8 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus ATCC 25923, E. faecalis 981 (MIC 18.8 uM), N. asteroides 201118 (MIC 2.3 uM), P.aeruginosa CGMCC 1.50 (inactive), K.pneumoniae 0804
Evidence 5 Activity

Activity

MIC
Antifungal
2.3 µM

Target

N. asteroides 201118

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against S. aureus ATCC 25923, E. faecalis 981 (MIC 18.8 uM), N. asteroides 201118 (MIC 2.3 uM), P.aeruginosa CGMCC 1.50 (inactive), K.pneumoniae 08040724 (inactive), E.coli ATCC 25922
Evidence 6 Activity

Activity

MIC
Antifungal
150 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

01118 (MIC 2.3 uM), P.aeruginosa CGMCC 1.50 (inactive), K.pneumoniae 08040724 (inactive), E.coli ATCC 25922 (MIC 150 uM), C.albicans ATCC 10231 (inactive), and C.glabrata 090902 (inactive). Updated 7/2021 4/20
Evidence 7 Activity

Activity

78.1% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
78.1% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 8 Activity

Activity

48.8% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
48.8% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 9 Activity

Activity

20.2% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
20.2% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 10 Activity

Activity

7.3% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
7.3% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 11 Activity

Activity

0% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
0% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 12 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.