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Peptide record

TPDB07192

Antibacterial Antifungal Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07192
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FLPFLAGLFGKIF
Physicochemical Analysis
C78H112N14O14
RNDCEQHMSTWYV
F
1469.83
10.10
1
0
9
+1
-5.22
1.738
127.69
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
1
I
3
L
1
K
0
M
4
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 3 K: 1 M: 0 F: 4 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C78H112N14O14
1469.83
10.10
+1
-5.22
1.738
Evidence Records 13 records
Evidence 1 Activity

Activity

MIC
Antibacterial
150 µM

Target

S.aureus ATCC 25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S.aureus ATCC 25923 (MIC 150 uM), E. faecalis 981 (MIC 18.8 uM), N. asteroides 201118 (MIC 75 uM), P.aeruginosa CGMCC 1.50
Evidence 2 Activity

Activity

MIC
Antibacterial
18.8 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP

Other

Active against S.aureus ATCC 25923 (MIC 150 uM), E. faecalis 981 (MIC 18.8 uM), N. asteroides 201118 (MIC 75 uM), P.aeruginosa CGMCC 1.50 (inactive MIC>150 uM), K.pneu
Evidence 3 Activity

Activity

MIC
Antibacterial
75 µM

Target

N. asteroides 201118

Source & Reference

dbAMP

Other

Active against S.aureus ATCC 25923 (MIC 150 uM), E. faecalis 981 (MIC 18.8 uM), N. asteroides 201118 (MIC 75 uM), P.aeruginosa CGMCC 1.50 (inactive MIC>150 uM), K.pneumoniae 08040724 (inactive), E.coli
Evidence 4 Activity

Activity

MIC
Antifungal
150 µM

Target

S.aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S.aureus ATCC 25923 (MIC 150 uM), E. faecalis 981 (MIC 18.8 uM), N. asteroides 201118 (MIC 75 uM), P.aeruginosa CGMCC 1.50
Evidence 5 Activity

Activity

MIC
Antifungal
18.8 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against S.aureus ATCC 25923 (MIC 150 uM), E. faecalis 981 (MIC 18.8 uM), N. asteroides 201118 (MIC 75 uM), P.aeruginosa CGMCC 1.50 (inactive MIC>150 uM), K.pneu
Evidence 6 Activity

Activity

MIC
Antifungal
75 µM

Target

N. asteroides 201118

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against S.aureus ATCC 25923 (MIC 150 uM), E. faecalis 981 (MIC 18.8 uM), N. asteroides 201118 (MIC 75 uM), P.aeruginosa CGMCC 1.50 (inactive MIC>150 uM), K.pneumoniae 08040724 (inactive), E.coli
Evidence 7 Activity

Activity

78.0% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
78.0% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 8 Activity

Activity

77.8% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
77.8% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 9 Activity

Activity

77.4% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
77.4% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 10 Activity

Activity

64.8% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
64.8% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 11 Activity

Activity

33.3% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
33.3% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 12 Activity

Activity

7.9% Hemolysis
Toxicity
6.3 µM
Hemolytic Cytotoxic
7.9% Hemolysis | 6.3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 13 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.