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Peptide record

TPDB07180

Antibacterial Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07180
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RERSKGSKYLYVG
Physicochemical Analysis
C68H111N21O20
ANDCQHIMFPTW
RGKSY
1542.76
10.36
4
1
4
+3
3.53
-1.331
52.31
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
2980
193.16
4
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
1
E
0
Q
2
G
0
H
0
I
1
L
2
K
0
M
0
F
0
P
2
S
0
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 0 I: 0 L: 1 K: 2 M: 0 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 2 V: 1
Chemical Descriptors
13
C68H111N21O20
1542.76
10.36
+3
3.53
-1.331
Evidence Records 10 records
Evidence 1 Activity

Activity

MIC
Antibacterial
40 µM

Target

Staphylococcus aureus MTCC 3160 or MTCC 9542

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Moderately active against S. aureus MTCC 3160 or MTCC 9542 (MIC 40 uM), and weakly active against E. coli (MIC 81 uM), P.aeruginosa MTCC 8076 (MIC 162 uM) and V
Evidence 2 Activity

Activity

MIC
Antibacterial
81 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

ly active against S. aureus MTCC 3160 or MTCC 9542 (MIC 40 uM), and weakly active against E. coli (MIC 81 uM), P.aeruginosa MTCC 8076 (MIC 162 uM) and V. cholerae (MIC 81 uM). 125 ug/ml converted to
Evidence 3 Activity

Activity

MIC
Antibacterial
162 µM

Target

P.aeruginosa MTCC 8076

Source & Reference

dbAMP DRAMP

Other

aureus MTCC 3160 or MTCC 9542 (MIC 40 uM), and weakly active against E. coli (MIC 81 uM), P.aeruginosa MTCC 8076 (MIC 162 uM) and V. cholerae (MIC 81 uM). 125 ug/ml converted to 81 uM. Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antibacterial
81 µM

Target

V. cholerae

Source & Reference

dbAMP DRAMP

Other

), and weakly active against E. coli (MIC 81 uM), P.aeruginosa MTCC 8076 (MIC 162 uM) and V. cholerae (MIC 81 uM). 125 ug/ml converted to 81 uM. Updated 7/2021
Evidence 5 Activity

Activity

MIC
Antifungal
40 µM

Target

Staphylococcus aureus MTCC 3160 or MTCC 9542

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Moderately active against S. aureus MTCC 3160 or MTCC 9542 (MIC 40 uM), and weakly active against E. coli (MIC 81 uM), P.aeruginosa MTCC 8076 (MIC 162 uM) and V
Evidence 6 Activity

Activity

MIC
Antifungal
81 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP Antifungipept

Other

ly active against S. aureus MTCC 3160 or MTCC 9542 (MIC 40 uM), and weakly active against E. coli (MIC 81 uM), P.aeruginosa MTCC 8076 (MIC 162 uM) and V. cholerae (MIC 81 uM). 125 ug/ml converted to
Evidence 7 Activity

Activity

MIC
Antifungal
162 µM

Target

P.aeruginosa MTCC 8076

Source & Reference

dbAMP DRAMP Antifungipept

Other

aureus MTCC 3160 or MTCC 9542 (MIC 40 uM), and weakly active against E. coli (MIC 81 uM), P.aeruginosa MTCC 8076 (MIC 162 uM) and V. cholerae (MIC 81 uM). 125 ug/ml converted to 81 uM. Updated 7/2021
Evidence 8 Activity

Activity

MIC
Antifungal
81 µM

Target

V. cholerae

Source & Reference

dbAMP DRAMP Antifungipept

Other

), and weakly active against E. coli (MIC 81 uM), P.aeruginosa MTCC 8076 (MIC 162 uM) and V. cholerae (MIC 81 uM). 125 ug/ml converted to 81 uM. Updated 7/2021
Evidence 9 Activity

Activity

11% Hemolysis
Toxicity
300 µg/mL
Hemolytic Cytotoxic
11% Hemolysis | 300 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization of two novel antimicrobial peptides from the cuticular extracts of the ant Trichomyrmex criniceps (Mayr), (Hymenoptera: Formicidae). | Arch Insect Biochem Physiol | 2017
Evidence 10 Activity

Activity

18% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
18% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization of two novel antimicrobial peptides from the cuticular extracts of the ant Trichomyrmex criniceps (Mayr), (Hymenoptera: Formicidae). | Arch Insect Biochem Physiol | 2017