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Peptide record

TPDB07172

Antibacterial Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07172
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLLPLLSLLGKLL
Physicochemical Analysis
C66H120N14O15
ARNDCEQHIMFTWYV
L
1349.76
10.10
1
0
8
+1
-2.89
1.792
240.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
8
L
1
K
0
M
0
F
1
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 8 K: 1 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C66H120N14O15
1349.76
10.10
+1
-2.89
1.792
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
2 µM
Hemolytic Cytotoxic
50% Hemolysis | 2 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Ab initio design of potent anti-MRSA peptides based on database filtering technology. | J Am Chem Soc | 2012
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis