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Peptide record

TPDB07142

Antibacterial Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07142
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
FFGSLLKLLPKLL
Physicochemical Analysis
C76H125N15O15
ARNDCEQHIMTWYV
L
1488.92
10.60
2
0
8
+2
-3.05
1.369
180.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
6
L
2
K
0
M
2
F
1
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 6 K: 2 M: 0 F: 2 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C76H125N15O15
1488.92
10.60
+2
-3.05
1.369
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
25-50 µM
Hemolytic Cytotoxic
50% Hemolysis | 25-50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Ab initio design of potent anti-MRSA peptides based on database filtering technology. | J Am Chem Soc | 2012
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis