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Peptide record

TPDB07141

Antibacterial Anticancer Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07141
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FASGIAGMAGKLF
Physicochemical Analysis
C59H92N14O15S1
RNDCEQHPTWYV
AG
1269.52
10.10
1
0
8
+1
-2.72
1.177
83.08
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
1
I
1
L
1
K
1
M
2
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 1 K: 1 M: 1 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C59H92N14O15S1
1269.52
10.10
+1
-2.72
1.177
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Insight into the mechanism of action of temporin-SHa, a new broad-spectrum antiparasitic and antibacterial agent. | PLoS One | 2017
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
50% Hemolysis | >100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Insight into the mechanism of action of temporin-SHa, a new broad-spectrum antiparasitic and antibacterial agent. | PLoS One | 2017
Evidence 3 Activity

Activity

% Hemolysis
Toxicity
50 %
Hemolytic Cytotoxic
Hemolytic_activity: Rat erythrocytes: 50% Hemolysis>200µM Human erythrocytes: 50% Hemolysis >100µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
PLoS One. 2017 Mar 20 12(3):e0174024.