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Peptide record

TPDB07129

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07129
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ILKWKWKWWPWRR
Physicochemical Analysis
C102H141N27O14
ANDCEQGHMFSTYV
W
1969.41
12.43
5
0
7
+5
-5.08
-1.423
60.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
27500
1396.35
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
3
K
0
M
0
F
1
P
0
S
0
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 3 M: 0 F: 0 P: 1 S: 0 T: 0 W: 5 Y: 0 V: 0
Chemical Descriptors
13
C102H141N27O14
1969.41
12.43
+5
-5.08
-1.423
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
560 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 560 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of novel indolicidin-derived antimicrobial peptides with enhanced cell specificity and potent anti-inflammatory activity | Peptides | 2009
Evidence 2 Activity

Activity

HC50
Toxicity
560 µg/mL
Hemolytic
Hemolytic_activity: [Ref.19428758] HC50=560 µg/ml against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2009 May 30(5):832-8. doi: 10.1016/j.peptides.2009.01.015.