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Peptide record

TPDB07127

Antibacterial Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07127
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ILGKLWEGLKSLF
Physicochemical Analysis
C74H118N16O17
ARNDCQHMPTYV
L
1503.85
9.88
2
1
7
+1
-1.38
0.669
150.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
365.73
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
0
Q
2
G
0
H
1
I
4
L
2
K
0
M
1
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 0 I: 1 L: 4 K: 2 M: 0 F: 1 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C74H118N16O17
1503.85
9.88
+1
-1.38
0.669
Evidence Records 4 records
Evidence 1 Activity

Activity

80% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
80% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial Activity and Toxicity of Analogs of Scorpion Venom IsCT Peptides. | Antibiotics (Basel) | 2017
Evidence 2 Activity

Activity

90% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
90% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial Activity and Toxicity of Analogs of Scorpion Venom IsCT Peptides. | Antibiotics (Basel) | 2017
Evidence 3 Activity

Activity

% Hemolysis
Toxicity
1 %
Hemolytic
Hemolytic_activity: [Ref.28657596] 1% hemolysis at 10 µg/ml, 78% hemolysis at 50 µg/ml, 90% hemolysis at 100 µg/ml against human red cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Antibiotics (Basel). 2017 Jun 28 6(3).
Evidence 4 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis