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Peptide record

TPDB07126

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07126
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
ILGKIWKPIKKLF
Physicochemical Analysis
C81H134N18O14
ARNDCEQHMSTYV
K
1584.07
11.00
4
0
7
+4
-0.61
0.415
150.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
347.21
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
2
L
4
K
0
M
1
F
1
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 2 K: 4 M: 0 F: 1 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C81H134N18O14
1584.07
11.00
+4
-0.61
0.415
Evidence Records 4 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibiotic activity and structural analysis of the scorpion-derived antimicrobial peptide IsCT and its analogs. | Biochem Biophys Res Commun | 2004
Evidence 2 Activity

Activity

Toxicity
Hemolytic
NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
QSAR Reveals Decreased Lipophilicity of Polar Residues Determines the Selectivity of Antimicrobial Peptide Activity. | ACS Omega | 2024
Evidence 3 Activity

Activity

LC90
Toxicity
256 µg/mL
Cytotoxic
LC90 | 256 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
QSAR Reveals Decreased Lipophilicity of Polar Residues Determines the Selectivity of Antimicrobial Peptide Activity. | ACS Omega | 2024
Evidence 4 Activity

Activity

LC50
Toxicity
142.5 µg/mL
Cytotoxic
LC50 | 142.5 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
QSAR Reveals Decreased Lipophilicity of Polar Residues Determines the Selectivity of Antimicrobial Peptide Activity. | ACS Omega | 2024