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Peptide record

TPDB07125

Antibacterial Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07125
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
ILGKIWKGIKNIL
Physicochemical Analysis
C73H126N18O15
ARDCEQHMFPSTYV
I
1495.91
10.84
3
0
7
+3
-0.80
0.669
180.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
367.67
1
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
4
I
2
L
3
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 4 L: 2 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C73H126N18O15
1495.91
10.84
+3
-0.80
0.669
Evidence Records 13 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12 µM

Target

Staphylococcus aureus AB 94004

Source & Reference

NA

Other

Active against Gram+ S. aureus AB 94004 (MIC 12 uM) B. megaterium AB 90008 (MIC 50 uM) M. luteus AB2010179 (MIC 2 uM) Gram- E. coli DH5alp
Evidence 2 Activity

Activity

MIC
Antibacterial
50 µM

Target

B. megaterium AB 90008

Source & Reference

NA

Other

Active against Gram+ S. aureus AB 94004 (MIC 12 uM) B. megaterium AB 90008 (MIC 50 uM) M. luteus AB2010179 (MIC 2 uM) Gram- E. coli DH5alpha (MIC 82 uM), P. fluorences PF (MI
Evidence 3 Activity

Activity

MIC
Antibacterial
2 µM

Target

M. luteus AB2010179

Source & Reference

NA

Other

Active against Gram+ S. aureus AB 94004 (MIC 12 uM) B. megaterium AB 90008 (MIC 50 uM) M. luteus AB2010179 (MIC 2 uM) Gram- E. coli DH5alpha (MIC 82 uM), P. fluorences PF (MIC 32 uM), P. putida PP (MIC 16 u
Evidence 4 Activity

Activity

MIC
Antibacterial
82 µM

Target

Escherichia coli DH5alpha

Source & Reference

NA

Other

04 (MIC 12 uM) B. megaterium AB 90008 (MIC 50 uM) M. luteus AB2010179 (MIC 2 uM) Gram- E. coli DH5alpha (MIC 82 uM), P. fluorences PF (MIC 32 uM), P. putida PP (MIC 16 uM), E. cloacae AB 2010162 (MIC 40 uM
Evidence 5 Activity

Activity

MIC
Antibacterial
32 µM

Target

P. fluorences PF

Source & Reference

NA

Other

AB 90008 (MIC 50 uM) M. luteus AB2010179 (MIC 2 uM) Gram- E. coli DH5alpha (MIC 82 uM), P. fluorences PF (MIC 32 uM), P. putida PP (MIC 16 uM), E. cloacae AB 2010162 (MIC 40 uM), S. enterica AB 2010185 (MIC
Evidence 6 Activity

Activity

MIC
Antibacterial
16 µM

Target

P. putida PP

Source & Reference

NA

Other

s AB2010179 (MIC 2 uM) Gram- E. coli DH5alpha (MIC 82 uM), P. fluorences PF (MIC 32 uM), P. putida PP (MIC 16 uM), E. cloacae AB 2010162 (MIC 40 uM), S. enterica AB 2010185 (MIC 35 uM), and E-cloacae AB
Evidence 7 Activity

Activity

MIC
Antibacterial
40 µM

Target

Enterobacter cloacae AB 2010162

Source & Reference

NA

Other

am- E. coli DH5alpha (MIC 82 uM), P. fluorences PF (MIC 32 uM), P. putida PP (MIC 16 uM), E. cloacae AB 2010162 (MIC 40 uM), S. enterica AB 2010185 (MIC 35 uM), and E-cloacae AB 2010162 (MIC>82 uM).
Evidence 8 Activity

Activity

MIC
Antibacterial
35 µM

Target

S. enterica AB 2010185

Source & Reference

NA

Other

. fluorences PF (MIC 32 uM), P. putida PP (MIC 16 uM), E. cloacae AB 2010162 (MIC 40 uM), S. enterica AB 2010185 (MIC 35 uM), and E-cloacae AB 2010162 (MIC>82 uM).
Evidence 9 Activity

Activity

1.7% Hemolysis
Toxicity
6 µM
Hemolytic Cytotoxic
1.7% Hemolysis | 6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Genomic and functional characterization of three new venom peptides from the scorpion Heterometrus spinifer. | Peptides | 2014
Evidence 10 Activity

Activity

19.1% Hemolysis
Toxicity
12 µM
Hemolytic Cytotoxic
19.1% Hemolysis | 12 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Genomic and functional characterization of three new venom peptides from the scorpion Heterometrus spinifer. | Peptides | 2014
Evidence 11 Activity

Activity

31.9% Hemolysis
Toxicity
24 µM
Hemolytic Cytotoxic
31.9% Hemolysis | 24 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Genomic and functional characterization of three new venom peptides from the scorpion Heterometrus spinifer. | Peptides | 2014
Evidence 12 Activity

Activity

56.6% Hemolysis
Toxicity
48 µM
Hemolytic Cytotoxic
56.6% Hemolysis | 48 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Genomic and functional characterization of three new venom peptides from the scorpion Heterometrus spinifer. | Peptides | 2014
Evidence 13 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis