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Peptide record

TPDB07103

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07103
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GLFDIVKKVVGAL
Physicochemical Analysis
C65H111N15O16
RNCEQHMPSTWY
V
1358.69
9.88
2
1
8
+1
0.71
1.323
164.62
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
0
E
0
Q
2
G
0
H
1
I
2
L
2
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 2 K: 2 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
13
C65H111N15O16
1358.69
9.88
+1
0.71
1.323
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Aurein-derived antimicrobial peptides formulated with pegylated phospholipid micelles to target methicillin-resistant Staphylococcus aureus skin infections. | ACS Infect Dis | 2018
Evidence 2 Activity

Activity

15% Cytotoxicity
Toxicity
50 µg/mL
Cytotoxic
15% Cytotoxicity | 50 | µg/mL | target cell: Human PBMC

Target

Human PBMC

Source & Reference

NA
DBAASP
Aurein-derived antimicrobial peptides formulated with pegylated phospholipid micelles to target methicillin-resistant Staphylococcus aureus skin infections. | ACS Infect Dis | 2018