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Peptide record

TPDB07073

Antibacterial Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07073
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
LKHGLLKRIKTLL
Physicochemical Analysis
C72H133N21O15
ANDCEQMFPSWYV
L
1532.98
11.73
5
0
6
+4
1.78
0.231
180.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
1
I
5
L
3
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 5 K: 3 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C72H133N21O15
1532.98
11.73
+4
1.78
0.231
Evidence Records 2 records
Evidence 1 Activity

Activity

30% Hemolysis
Toxicity
8 µM
Hemolytic Cytotoxic
30% Hemolysis | 8 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Copper-binding tripeptide motif increases potency of the antimicrobial peptide Anoplin via Reactive Oxygen Species generation. | Biochem Biophys Res Commun | 2015
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis