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Peptide record

TPDB07040

Antibacterial Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07040
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
RTHGLLKRIKTLL
Physicochemical Analysis
C70H129N23O16
ANDCEQMFPSWYV
L
1548.94
12.42
5
0
5
+4
2.30
-0.162
150.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
1
I
4
L
2
K
0
M
0
F
0
P
0
S
2
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 4 K: 2 M: 0 F: 0 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C70H129N23O16
1548.94
12.42
+4
2.30
-0.162
Evidence Records 2 records
Evidence 1 Activity

Activity

30% Hemolysis
Toxicity
8 µM
Hemolytic Cytotoxic
30% Hemolysis | 8 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Copper-binding tripeptide motif increases potency of the antimicrobial peptide Anoplin via Reactive Oxygen Species generation. | Biochem Biophys Res Commun | 2015
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis